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Merck

860460P

Avanti

N-C12-deoxysphinganine

N-lauroyl-1-deoxysphinganine (m18:0/12:0), powder

别名:

N-dodecanoyl-1-deoxysphinganine (m18:0/12:0); N-C12-1-deoxyDHCer; 110958

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About This Item

经验公式(希尔记法):
C30H61NO2
分子量:
467.81
分類程式碼代碼:
12352211

化驗

>99% (TLC)

形狀

powder

包裝

pkg of 1 × 1 mg (860460P-1mg)

製造商/商標名

Avanti Research - A Croda Brand 860460P

運輸包裝

dry ice

儲存溫度

−20°C

一般說明

Commonly referred to as 1-deoxydihydroceramide (1-deoxyDHCer), this product is the N-acylated form of 1-deoxysphinganine, a potent inhibitor of sphingolipid metabolism. The biological activity of 1-deoxyDHCer is not clearly understood at this time.
N-C12-deoxysphinganine is found in mammalian cells. It may be associated with neuronal toxicity.

包裝

5 mL Amber Glass Screw Cap Vial (860460P-1mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3


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Quantifying 1-deoxydihydroceramides and 1-deoxyceramides in mouse nervous system tissue
Schwartz NU, et al.
Prostaglandins & other lipid mediators (2019)
Ceramide synthase inhibition by fumonisin B1 causes accumulation of 1-deoxysphinganine a novel category of bioactive 1-deoxysphingoid bases and 1-deoxydihydroceramides biosynthesized by mammalian cell lines and animals
Zitomer NC, et al.
The Journal of Biological Chemistry, 284(8), 4786-4795 (2009)

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