857133C

18:1 BMP (S,R)

bis(monooleoylglycero)phosphate (S,R Isomer) (ammonium salt), chloroform

• 别名: sn-(3--(9Z-octadecenoyl)-2-hydroxy)-glycerol-1-phospho-sn-3′-(1′--(9Z-octadecenoyl)-2′-hydroxy)-glycerol (ammonium salt); lysobisphosphatidic acid; LBPA; 110729
• 经验公式（希尔记法）: C₄₂H₈₂NO₁₀P
• CAS号: 326495-20-9
• 分子量: 792.07
• UNSPSC代码: 51191904
• NACRES: NA.25

属性

• 方案: >99% (BMP (contains 30% positional isomers), TLC)
• 表单: liquid
• 包装: pkg of 1 × 1 mL (857133C-5mg); pkg of 1 × 2 mL (857133C-50mg)
• 制造商/商品名称: Avanti Research^™ - A Croda Brand 857133C
• 浓度: 25 mg/mL (857133C-50mg); 5 mg/mL (857133C-5mg)
• 脂质类型: cardiolipins; phospholipids
• 运输: dry ice
• 储存温度: −20°C
• SMILES字符串: [H][C@@](COP(OC[C@@]([H])(O)COC(CCCCCCC/C=C\CCCCCCCC)=O)([O-])=O)(O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+]
• InChI: 1S/C42H79O10P.H3N/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-41(45)49-35-39(43)37-51-53(47,48)52-38-40(44)36-50-42(46)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h17-20,39-40,43-44H,3-16,21-38H2,1-2H3,(H,47,48);1H3/b19-17-,20-18-;/t39-,40+;
• InChI key: YRFISMFFADMBIY-RVSVVSAUSA-N

说明

一般描述

Bis(monoacylglycerol)phosphate (BMP), an acidic phospholipid is mostly found in the lysosomal and endosomal compartments within cells.

应用

18:1 BMP (S,R) is suitable for the analysis of Niemann-Pick C2 (NPC2)-lipid interaction.

生化/生理作用

Bis(monoacylglycerol)phosphate (BMP) plays a vital role in late endosomes/lysosomes (LE/Lys) degradation pathway. It is involved in digestion and recycling of membranous materials and synthesis of intra luminal vesicles. BMP also regulates cholesterol homeostasis and trafficking of lysosomal enzymes.

包装

5 mL Clear Glass Sealed Ampule (857133C-50mg)

5 mL Clear Glass Sealed Ampule (857133C-5mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全信息

• 象形图: GHS06,GHS08
• 警示用语：: Danger
• 危险声明: H302,H315,H319,H331,H336,H351,H361d,H372
• 预防措施声明: P202 - P301 + P312 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• 危险分类: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
• 靶器官: Liver,Kidney, Respiratory system
• WGK: WGK 3