830842P

08:0 PA

1,2-dioctanoyl-sn-glycero-3-phosphate (sodium salt), powder

• 别名: PA(8:0/8:0)
• 经验公式（希尔记法）: C₁₉H₃₆O₈PNa
• CAS号: 321883-54-9
• 分子量: 446.45
• MDL號碼: MFCD03788001
• 分類程式碼代碼: 51191904
• NACRES: NA.25

属性

• 化驗: >99% (TLC)
• 形狀: powder
• 包裝: pkg of 1 × 10 mg (830842P-10mg); pkg of 1 × 25 mg (830842P-25mg)
• 製造商／商標名: Avanti Research^™ - A Croda Brand 830842P
• 脂質類型: cardiolipins; phospholipids
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• SMILES 字串: [H][C@@](COP([O-])(O)=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O.[Na+]
• InChI: 1S/C19H37O8P.Na/c1-3-5-7-9-11-13-18(20)25-15-17(16-26-28(22,23)24)27-19(21)14-12-10-8-6-4-2;/h17H,3-16H2,1-2H3,(H2,22,23,24);/q;+1/p-1/t17-;/m1./s1
• InChI 密鑰: ZNDNSOYDPUTHKQ-UNTBIKODSA-M

说明

一般說明

Phosphatidic acid is obtained from glycerophospholipid with the help of phospholipase D. 08:0 PA/1,2-dioctanoyl-sn-glycero-3-phosphate (C8-PA) is an mammalian target of rapamycin (mTOR) activator.

應用

08:0 PA may be used to activate p-mTOR in order to assess whether the observed apoptotic effect of histone deacetylase inhibitors (HDACIs) is related to mammalian target of rapamycin (mTOR) pathway signaling.

生化／生理作用

Phosphatidic acid might serve as a modulator of phagocyte respiratory burst. It also acts as a precursor of diacylglycerol and lysophosphatidic acid. 08:0 PA/C8-PA has the ability to affect the phosphorylation of mammalian target of rapamycin (mTOR) and the viability of gallbladder carcinoma cells, that are treated with histone deacetylase inhibitors (HDACIs).

包裝

5 mL Clear Glass Sealed Ampule (830842P-10mg)

5 mL Clear Glass Sealed Ampule (830842P-25mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全信息

• 儲存類別代碼: 11 - Combustible Solids