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Merck
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主要文件

810110P

Avanti

12-NBD Stearate

Avanti Research - A Croda Brand 810110P, powder

别名:

12-N-methyl-(7-nitrobenz-2-oxa-1,3-diazo)aminostearic acid

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About This Item

经验公式(希尔记法):
C25H40N4O5
分子量:
476.61
MDL號碼:
分類程式碼代碼:
12352211
NACRES:
NA.25

化驗

>99% (TLC)

形狀

powder

包裝

pkg of 1 × 1 mg (810110P-1mg)

製造商/商標名

Avanti Research - A Croda Brand 810110P

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[N+](=O)([O-])c1c2n[o]nc2c(cc1)N(C(CCCCCCCCCCC(=O)O)CCCCCC)C

InChI

1S/C25H40N4O5/c1-3-4-5-12-15-20(16-13-10-8-6-7-9-11-14-17-23(30)31)28(2)21-18-19-22(29(32)33)25-24(21)26-34-27-25/h18-20H,3-17H2,1-2H3,(H,30,31)

InChI 密鑰

SAAVELCIPHKGJE-UHFFFAOYSA-N

一般說明

12-NBD Stearate is amphipathic, nonesterifiable fluorescent fatty acid probe and is a long-chain fatty acid (LCFA) derivative.

應用

12-NBD Stearate has been used in the fluorescent labeling of omega-3 fatty acid in biomaterial films and as a ligand for fatty acid binding protein 5 (FABP5) in competitive binding based high throughput fluorescence displacement assay. It may be used a ligand fluorescence displacement assay of fatty-acid binding protein 5 (FABP5).

生化/生理作用

12-NBD Stearate incorporated in lipid droplets and is used majorly in fluorescence displacement binding studies of fatty-acid binding proteins. The sterol carrier protein-2 (SCP-2) 15-kDa isoform favours NBD Stearate transport. The uptake of NBD Stearate is regulated by fatty acid binding protein (FABP) expression regulates uptake and inhibited by filipin III.

包裝

5 mL Amber Glass Screw Cap Vial (810110P-1mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Tracking of drug release and material fate for naturally derived omega-3 fatty acid biomaterials
Faucher KM, et al.
Annals of Biomedical Engineering, 44(3), 782-792 (2016)
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ACS infectious diseases, 6(4), 637-648 (2020-02-14)
Assembly of the bacterial cell wall requires not only the biosynthesis of cell wall components but also the transport of these metabolites to the cell exterior for assembly into polymers and membranes required for bacterial viability and virulence. LprG is
Targeting fatty acid binding protein (FABP) anandamide transporters-a novel strategy for development of anti-inflammatory and anti-nociceptive drugs
Berger WT, et al.
Testing, 7(12) (2012)
Targeting fatty acid binding protein (FABP) anandamide transporters-a novel strategy for development of anti-inflammatory and anti-nociceptive drugs
Berger WT, et al.
PLoS ONE, 7(12) (2012)
FABP1: a novel hepatic endocannabinoid and cannabinoid binding protein
Huang H, et al.
Biochemistry, 55(37), 5243-5255 (2016)

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