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化驗
>99% (TLC)
形狀
powder
包裝
pkg of 1 × 1 mg (700143P-1MG)
pkg of 1 × 100 μg (700143P-100ug)
pkg of 1 × 250 μg (700143P-250ug)
製造商／商標名
Avanti Research™ - A Croda Brand 700143P
運輸包裝
dry ice
儲存溫度
−20°C
一般說明
Alkyne cholesterol is used to trace cholesterol metabolism and localization.
This reagent is a modified lipid containing an omega-terminal alkyne. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents, known as ‘click chemistry′, in the presence of a copper (Cu)-containing catalyst.
生化／生理作用
27-alkyne cholesterol acts similar to natural sterols such as, ergosterol and cholesterol.
包裝
5 mL Amber Glass Screw Cap Vial (700143P-1MG)
5 mL Amber Glass Screw Cap Vial (700143P-100ug)
5 mL Amber Glass Screw Cap Vial (700143P-250ug)
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
A novel alkyne cholesterol to trace cellular cholesterol metabolism and localization.
Hofmann K, et al.
Journal of Lipid Research, 55(3), 583-591 (2014)
Kristina Hofmann et al.
Journal of lipid research, 55(3), 583-591 (2013-12-18)
Cholesterol is an important lipid of mammalian cells and plays a fundamental role in many biological processes. Its concentration in the various cellular membranes differs and is tightly regulated. Here, we present a novel alkyne cholesterol analog suitable for tracing
Yaroslav V Faletrov et al.
Chemistry and physics of lipids, 227, 104850-104850 (2019-12-15)
20-hydroxycholesterol is a signaling oxysterol with immunomodulating functions and, thus, structural analogues with reporter capabilities could be useful for studying and modulating the cellular processes concerned. We have synthesized three new 20-hydroxycholesterol-like pregn-5-en-3β-ol derivatives with fluorescent 7-nitrobenzofurazan (NBD) or Raman-sensitive
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