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描述
7α,24(S)-dihydroxycholesterol
方案
>99% (TLC)
表单
powder
包装
pkg of 1 × 1 mg (700096P-1mg)
制造商/商品名称
Avanti Research™ - A Croda Brand
运输
dry ice
储存温度
−20°C
一般描述
7α,24(S)-dihydroxycholesterol (24(S)-dihydroxycholesterol) is synthetically synthesized via from E-α, β-enone from the starting compounds Arsonium ylide and J-tert-butyldimethylsilyloxy-bisnor-5-cholenaldehyde. This undergoes further changes to form 7α,24(S)-dihydroxycholesterol.
生化/生理作用
7α,24(S)-dihydroxycholesterol (24(S)-dihydroxycholesterol) is a ligand for liver X receptor (LXR) and binds to the ligand binding domain of LXRα and LXRβ.
包装
5 mL Amber Glass Screw Cap Vial (700096P-1mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
Simple, stereocontrolled syntheses of 24 (S), 25-epoxy-22 (R)-hydroxycholesterol, 22 (R), 24 (S)-dihydroxycholesterol and diastereomers, new ligands for binding and activation of LXRs
Corey EJ and Grogan MJ
Tetrahedron Letters, 39(51), 9355-9356 (1998)
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