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产品名称
N-羟基邻苯二甲酰亚胺, 97%
质量水平
方案
97%
表单
crystalline
反应适用性
reaction type: Addition Reactions
mp
233 °C (dec.) (lit.)
应用
peptide synthesis
SMILES字符串
ON1C(=O)c2ccccc2C1=O
InChI
1S/C8H5NO3/c10-7-5-3-1-2-4-6(5)8(11)9(7)12/h1-4,12H
InChI key
CFMZSMGAMPBRBE-UHFFFAOYSA-N
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应用
制备胺核苷，以用于偶联反应生成非阴离子反义寡聚核苷。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
其他客户在看
Tetrahedron Letters, 33, 2645-2645 (1992)
H M Petrassi et al.
Organic letters, 3(1), 139-142 (2001-06-30)
[figure: see text] A novel route to aryloxyamines via the copper-mediated cross-coupling of N-hydroxyphthalimide and phenylboronic acids is reported. The reaction is mediated by selected copper(I) and (II) salts in the presence of pyridine and is tolerant of several functional
[Hydroxyphthalimide induced medicamentosa-like dermatitis in five patients].
Jian-fang Zou et al.
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 24(10), 625-625 (2006-11-14)
James M Takacs et al.
Organic letters, 5(20), 3595-3598 (2003-09-26)
[reaction: see text] Screening combinations of five catalyst precursors with 13 phosphorus ligands identified cyclization catalysts that favor carbocyclization-trapping with N-hydroxyphthalimide over a competing cycloisomerization mode.
M H Lang et al.
Dermatosen in Beruf und Umwelt. Occupation and environment, 35(6), 212-213 (1987-11-01)
We report a case of a female laboratory worker in the chemical industry who acquired contact allergy to dicyclohexylcarbodiimide and N-hydroxyphthalimide. Both substances are used in the chemical synthesis of peptides. So far there have only been a few reports
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