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Merck

D157805

Sigma-Aldrich

N,N′-二甲基乙二胺

98%

别名:

DMEDA, 1,2-双(甲氨基)乙烷

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About This Item

线性分子式:
CH3NHCH2CH2NHCH3
CAS号:
分子量:
88.15
Beilstein:
878142
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

98%

形狀

liquid

折射率

n20/D 1.431 (lit.)

bp

119 °C (lit.)

密度

0.819 g/mL at 20 °C (lit.)

SMILES 字串

CNCCNC

InChI

1S/C4H12N2/c1-5-3-4-6-2/h5-6H,3-4H2,1-2H3

InChI 密鑰

KVKFRMCSXWQSNT-UHFFFAOYSA-N

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應用

N,N′-二甲基乙二胺可用作以下过程的配体:
  • 铜催化铁氰化钾参与的芳基溴代物的氰化反应,形成相应的苄腈。
  • 铜催化碳化二亚胺和异氰基乙酸酯的串联反应,形成苯并咪唑[1,5-α]咪唑。
  • 1,1-二溴烯烃的氨基硫化反应,形成N-稠杂环。
  • 与氯化亚铁结合,用于NH-亚砜亚胺与芳基碘化物的N-芳基化反应,形成N-芳基亚砜亚胺。
  • 丁醇钾存在下,它可催化未活化苯的直接C-H芳基化反应,形成相应的联芳基。

象形圖

FlameCorrosion

訊號詞

Danger

危險聲明

危險分類

Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

78.8 °F - closed cup

閃點(°C)

26 °C - closed cup

個人防護裝備

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Organocatalysis in cross-coupling: DMEDA-catalyzed direct C? H arylation of unactivated benzene.
Liu W, et al.
Journal of the American Chemical Society, 132(47), 16737-16740 (2010)
Copper-catalyzed synthesis of N-fused heterocycles through regioselective 1, 2-aminothiolation of 1, 1-dibromoalkenes.
Xu H, et al.
Organic Letters, 12(16), 3704-3707 (2010)
Generation of benzoimidazo [1, 5-a] imidazoles via a copper-catalyzed tandem reaction of carbodiimide and isocyanoacetate.
Qiu G, et al.
Chemical Communications (Cambridge, England), 48(48), 6046-6048 (2012)
Ghotas Evindar et al.
The Journal of organic chemistry, 71(5), 1802-1808 (2006-02-25)
A general method for the formation of benzoxazoles via a copper-catalyzed cyclization of ortho-haloanilides is reported. This approach complements the more commonly used strategies for benzoxazole formation which require 2-aminophenols as substrates. The reaction involves an intramolecular C-O cross-coupling of
Kim A Lennox et al.
Oligonucleotides, 16(1), 26-42 (2006-04-06)
A wide variety of modified oligonucleotides have been tested as antisense agents. Each chemical modification produces a distinct profile of potency, toxicity, and specificity. Novel cationic phosphoramidate-modified antisense oligonucleotides have been developed recently that have unique and interesting properties. We

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