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Merck

A8309

Sigma-Aldrich

乙酰肼

90%

别名:

Acetic acid hydrazide, Acetylhydrazine

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About This Item

线性分子式:
CH3CONHNH2
CAS号:
分子量:
74.08
Beilstein:
506165
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

质量水平

方案

90%

表单

flakes

杂质

<10% acetic acid

沸点

129 °C/18 mmHg (lit.)

mp

58-68 °C (lit.)

SMILES字符串

CC(=O)NN

InChI

1S/C2H6N2O/c1-2(5)4-3/h3H2,1H3,(H,4,5)

InChI key

OFLXLNCGODUUOT-UHFFFAOYSA-N

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一般描述

乙酰肼是一种有机合成砌块,可通过催化氢化反应生成 N′-甲基乙酰肼(MAH)。

应用

乙酰乙肼可用于合成(E)-N′-(2-羟基亚苄基)乙酰肼,这是一种 ONO 钳形配体。

象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

危险分类

Acute Tox. 3 Oral - Carc. 2 - Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

闪点(°F)

235.4 °F - closed cup

闪点(°C)

113 °C - closed cup

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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其他客户在看

Liquid phase hydrogenation of acethydrazone to N'-methyl acethydrazide over Pd/?-Al2O3 catalyst
Pakdehi SG, et al.
Brazilian Journal of Chemical Engineering, 27, 145-152 (2010)
Analysis of isoniazid, acetylhydrazine and [15N2]acetylhydrazine in serum by capillary gas chromatography-ammonia chemical ionization mass spectrometry.
G Karlaganis et al.
Journal of chromatography, 420(1), 171-177 (1987-09-04)
T C Sarich et al.
Archives of toxicology, 70(12), 835-840 (1996-01-01)
Isoniazid (INH) continues to be a highly effective drug in the chemoprophylaxis and treatment of tuberculosis; however, its use is associated with hepatotoxicity (predominantly hepatic necrosis) in 1-2% of individuals. The INH metabolites, acetylhydrazine and hydrazine, have each been implicated
A Walubo et al.
Methods and findings in experimental and clinical pharmacology, 20(8), 649-655 (1999-01-29)
Isoniazid and its metabolites acetylisoniazid, hydrazine and monoacetylhydrazine were investigated for generation of oxygen free radicals during incubation with rat liver slices. Lipid peroxidation was assessed by the thiobarbituric acid reactive substances test using malonaldehyde as the external standard, while
N E Preece et al.
Journal of chromatography, 573(2), 227-234 (1992-01-17)
Plasma and liver levels of hydrazine were determined at 10, 30, 90 and 270 min in rats given 0.09, 0.27, 0.84 and 2.53 mmol of hydrazine per kg body weight orally by capillary gas chromatography-mass spectrometry of its pentafluorobenzaldehyde adduct

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