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品質等級
化驗
90%
形狀
flakes
雜質
<10% acetic acid
bp
129 °C/18 mmHg (lit.)
mp
58-68 °C (lit.)
SMILES 字串
CC(=O)NN
InChI
1S/C2H6N2O/c1-2(5)4-3/h3H2,1H3,(H,4,5)
InChI 密鑰
OFLXLNCGODUUOT-UHFFFAOYSA-N
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一般說明
乙酰肼是一种有机合成砌块,可通过催化氢化反应生成 N′-甲基乙酰肼(MAH)。
應用
乙酰乙肼可用于合成(E)-N′-(2-羟基亚苄基)乙酰肼,这是一种 ONO 钳形配体。
訊號詞
Danger
危險分類
Acute Tox. 3 Oral - Carc. 2 - Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類(WGK)
WGK 1
閃點(°F)
235.4 °F - closed cup
閃點(°C)
113 °C - closed cup
個人防護裝備
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
其他客户在看
Liquid phase hydrogenation of acethydrazone to N'-methyl acethydrazide over Pd/?-Al2O3 catalyst
Pakdehi SG, et al.
Brazilian Journal of Chemical Engineering, 27, 145-152 (2010)
T C Sarich et al.
Archives of toxicology, 70(12), 835-840 (1996-01-01)
Isoniazid (INH) continues to be a highly effective drug in the chemoprophylaxis and treatment of tuberculosis; however, its use is associated with hepatotoxicity (predominantly hepatic necrosis) in 1-2% of individuals. The INH metabolites, acetylhydrazine and hydrazine, have each been implicated
Analysis of isoniazid, acetylhydrazine and [15N2]acetylhydrazine in serum by capillary gas chromatography-ammonia chemical ionization mass spectrometry.
G Karlaganis et al.
Journal of chromatography, 420(1), 171-177 (1987-09-04)
A Walubo et al.
Methods and findings in experimental and clinical pharmacology, 20(8), 649-655 (1999-01-29)
Isoniazid and its metabolites acetylisoniazid, hydrazine and monoacetylhydrazine were investigated for generation of oxygen free radicals during incubation with rat liver slices. Lipid peroxidation was assessed by the thiobarbituric acid reactive substances test using malonaldehyde as the external standard, while
D J Fort et al.
Teratogenesis, carcinogenesis, and mutagenesis, 10(6), 463-476 (1990-01-01)
The developmental toxicity of isoniazid (INH) and the metabolites acetylhydrazide (AH) and isonicotinic acid (INA) were examined with the frog embryo teratogenesis assay-Xenopus (FETAX). Late Xenopus laevis blastulae were exposed to INH, AH, and INA for 96 h in two
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