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Merck

A10507

Sigma-Aldrich

丙酮肟

98%

别名:

β-异亚硝基丙烷, 2-丙酮肟, N-异丙基亚基羟胺, 丙酮肟, 二甲基酮肟

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About This Item

线性分子式:
(CH3)2C=NOH
CAS号:
分子量:
73.09
Beilstein:
1560146
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.02

质量水平

方案

98%

表单

crystals

沸点

135 °C (lit.)

mp

60-63 °C (lit.)

密度

0.901 g/mL at 25 °C (lit.)

SMILES字符串

C\C(C)=N/O

InChI

1S/C3H7NO/c1-3(2)4-5/h5H,1-2H3

InChI key

PXAJQJMDEXJWFB-UHFFFAOYSA-N

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Danger

危险分类

Acute Tox. 4 Dermal - Carc. 2 - Eye Dam. 1 - Flam. Sol. 2 - Skin Sens. 1B

储存分类代码

4.1B - Flammable solid hazardous materials

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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N Guo et al.
Carcinogenesis, 11(9), 1659-1662 (1990-09-01)
The hepatocarcinogens 2-nitropropane and acetoxime have previously been found to induce a specific and qualitatively identical pattern of base damage in rat liver DNA and RNA, including the induction of increased levels of 8-hydroxyguanine. Because both 2-nitropropane and acetoxime are
J Torreilles et al.
Biochimie, 65(4-5), 295-298 (1983-04-01)
Preparation of adducts from nicotinamide adenine dinucleotide and a number of oximes is described; these include acetoxime, pyruvatoxime, cyclohexanoxime, cyclopentanoxime. These adducts are closely related to the corresponding NAD-ketone adducts in their spectra properties, but they are stable in acid
S S Mirvish et al.
Cancer letters, 41(2), 211-216 (1988-08-15)
We tested the ability of phenobarbital and two liver carcinogens, acetoxime and 1-nitroso-5,6-dihydrouracil (NDHU), to induce hyperplastic liver nodules (HLN) in MRC-Wistar and Wistar rats, using a system that included a single diethylnitrosamine (DEN) treatment, partial hepatectomy, and administration of
M Rysková et al.
Folia biologica, 43(1), 19-24 (1997-01-01)
The genotoxic effects of N-nitroso-N-methylurea (MNU) and acetone oxime (ACOX) were tested in the Somatic Mutation and Recombination Test (SMART) in Drosophila melanogaster. We have performed the same assay on transgenic flies expressing the human gene encoding a glutathione S-transferase
C Kohl et al.
Carcinogenesis, 13(7), 1091-1094 (1992-07-01)
The hepatocarcinogenicity of acetoxime has been tentatively linked with its metabolic oxidation to the potent genotoxicant and carcinogen propane 2-nitronate (P2-N). In order to test the hypothesis that acetoxime is metabolized to P2-N, the oxime (20 mM) was incubated with

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