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Merck

920401

Sigma-Aldrich

Methoxypolyethylene glycol

average MN 1,000 (by NMR), (Propionic acid), methoxy

别名:

O-(2-Carboxyethyl)-O′-methylpolyethylene glycol 1,000, PEG acid, PEG carboxylic acid, Polyethylene glycol, mPEG-COOH, mono-Methyl polyethylene glycol 1′000 propionic acid

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About This Item

线性分子式:
CH3(OCH2CH2)nOCH2CH2COOH
分類程式碼代碼:
12352106
NACRES:
NA.23

product name

Methoxypolyethylene glycol 1,000 propionic acid,

形狀

solid

品質等級

分子量

average Mn 1,000 (by NMR)

顏色

white to off-white

Ω-end

(Propionic acid)

α-end

methoxy

聚合物結構

shape: linear
functionality: monofunctional

儲存溫度

2-8°C

應用

Methoxypolyethylene glycol 1,000 propionic acid is a pegylation agent used to conjugate proteins to reduce immunogenicity and prolong serum half-life of proteins and enzymes.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Andrea Fajdetić et al.
European journal of medicinal chemistry, 46(8), 3388-3397 (2011-05-24)
Synthesis, antibacterial activity and pharmacokinetic properties of a novel class of macrolide antibiotics-macrolones-derived from azithromycin, comprising oxygen atom(s) in the linker and either free or esterified quinolone 3-carboxylic group, are reported. Selected compounds showed excellent antibacterial potency towards key erythromycin
A Ton J Dirks et al.
Bioconjugate chemistry, 20(6), 1129-1138 (2009-05-21)
The Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) has recently proven to be a powerful synthetic tool in various fields of chemistry, including protein-polymer conjugation. In this article, we describe a fluorogenic CuAAC, which allows for efficient monitoring of protein-polymer conjugation. We show

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