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Merck
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文件

918741

Sigma-Aldrich

TissueFab® bioink 

(Gel)ma -VIS/405nm, low endotoxin

别名:

Bioink, GelMA, Gelatin methacrylamide, Gelatin methacrylate, Gelatin methacryloyl

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About This Item

分類程式碼代碼:
12352201
NACRES:
NA.23

品質等級

100

描述

suitable for 3D bioprinting applications
with LAP photoinitiator

無菌

sterile-filtered

形狀

viscous liquid

雜質

≤5 CFU/g Bioburden (Fungal)
≤5 CFU/g Bioburden (Total Aerobic)
<50 EU/mL Endotoxin

顏色

colorless to pale yellow

粒徑

0.2 μm

pH值

6.5-7.5

應用

3D bioprinting

儲存溫度

2-8°C

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應用

TissueFab® GelMA-Vis-LAP bioink is a gelatin methacryloyl (GelMA) based bioink for 3D bioprinting applications. LAP is used as the photoinitiator, which allows blue light photocrosslinking of the printed structure. The formulation is optimized for high printing fidelity and cell viability. The low endotoxin level of this product is lower than 50 EU/mL.

Gelatin methacryloyl (GelMA) is a polymerizable hydrogel material derived from natural extracellular matrix (ECM) components. Due to its low cost, abundance, and retention of natural cell binding motifs, gelatin has become a highly sought material for tissue engineering applications. The addition of photocrosslinkable methacrylamide functional groups in GelMA allows the synthesis of biocompatible, biodegradable, and non-immunogenic hydrogels that are stable in biologically relevant conditions and promote cell adhesion, spreading, and proliferation.

法律資訊

TISSUEFAB is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

10 - Combustible liquids

水污染物質分類（WGK）

WGK 3

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Wanjun Liu et al.
Advanced healthcare materials, 6(12) (2017-05-04)
Bioprinting is an emerging technique for the fabrication of 3D cell-laden constructs. However, the progress for generating a 3D complex physiological microenvironment has been hampered by a lack of advanced cell-responsive bioinks that enable bioprinting with high structural fidelity, particularly
Birgit Huber et al.
Journal of biomaterials applications, 30(6), 699-710 (2015-05-29)
In vitro engineering of autologous fatty tissue constructs is still a major challenge for the treatment of congenital deformities, tumor resections or high-graded burns. In this study, we evaluated the suitability of photo-crosslinkable methacrylated gelatin (GM) and mature adipocytes as components
Y Shi et al.
Biomedical materials (Bristol, England), 13(3), 035008-035008 (2018-01-09)
Three-dimensional bioprinting is an emerging technology for fabricating living 3D constructs, and it has shown great promise in tissue engineering. Bioinks are scaffold materials mixed with cells used by 3D bioprinting to form a required cell-laden structure. In this paper
B Duan et al.
Acta biomaterialia, 10(5), 1836-1846 (2013-12-18)
Tissue engineering has great potential to provide a functional de novo living valve replacement, capable of integration with host tissue and growth. Among various valve conduit fabrication techniques, three-dimensional (3-D) bioprinting enables deposition of cells and hydrogels into 3-D constructs
Wanjun Liu et al.
Biofabrication, 10(2), 024102-024102 (2017-11-28)
Bioinks with shear-thinning/rapid solidification properties and strong mechanics are usually needed for the bioprinting of three-dimensional (3D) cell-laden constructs. As such, it remains challenging to generate soft constructs from bioinks at low concentrations that are favorable for cellular activities. Herein
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