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形狀
solid
分子量
PEG Mn 10K
PEG average Mn 10,000
generation 5
號表面基團
64
顏色
white to off-white
官能基
carboxylic acid
儲存溫度
−20°C
一般說明
- Polymer architecture: PEG-core dendrimer
- Bis-MPA : 2,2-Bis(hydroxymethyl)propionic acid
應用
Bis-MPA dendritic molecules are based on 2,2-bismethylolpropionicacid (bis-MPA) building blocks. The hydrolyzable linker allows for degradation into byproducts that can be reabsorbed by the body or into excretable non-toxic small molecules. This dendritic polymer is biocompatible, biodegradable, and suitable for biomedical applications. PEG-core dendrimers feature excellent solubility in water and a high degree of functionality per PEG chain, enable use for advanced drug delivery systems or for drug targeting. The carboxylic acid-functionalized corona can be readily used for bioconjugation reactions.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Chemistry of multifunctional polymers based on bis-MPA and their cutting-edge applications
Garcia-Gallego S, et al
Progress in Polymer Science, 48, 85?110-85?110 (2015)
Anna Carlmark et al.
Chemical Society reviews, 42(13), 5858-5879 (2013-05-01)
Dendritic polymers are highly branched, globular architectures with multiple representations of functional groups. These nanoscale organic frameworks continue to fascinate researchers worldwide and are today under intensive investigation in application-driven research. A large number of potential application areas have been
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Dendritic molecules' biomedical applications, particularly bis-MPA dendritic scaffolds, hold promise for drug delivery.
Dendrimers, polymer nanostructures, are synthesized for specific purposes by manipulating critical nanoscale design parameters (CNDPs).
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