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Merck

909696

Sigma-Aldrich

2-(tert-Butylsulfonyl)-1-phenylpropan-1-one

≥95%

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About This Item

经验公式(希尔记法):
C13H18O3S
分子量:
254.35
分類程式碼代碼:
12352005

化驗

≥95%

形狀

powder

反應適用性

reaction type: C-C Bond Formation

mp

121-124 °C

儲存溫度

−20°C

應用

2-(tert-Butylsulfonyl)-1-phenylpropan-1-one is part of a suite of reagents developed by the Li group for late-stage functionalization of pharmaceutically relevant compounds. The reagents serve as precursors to alkyl radicals generated under light mediated, redox-neutral and catalyst free conditions for use in the Minisci alkylation of aromatics.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Peng Liu et al.
Journal of the American Chemical Society, 139(40), 14315-14321 (2017-10-03)
The Minisci alkylation is useful to functionalize aromatics via alkyl radical addition. Current approaches to prepare alkyl radicals follow either oxidative or reductive pathways from various functional groups. Developing new strategy beyond these traditional methods remains elusive yet highly significant.

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