表单
powder
投料比
lactide:glycolide 80:20
分子量
PEG average Mn 5,000
PLGA Mn 5,000
杂质
≤5000 ppm (GC)
运输
dry ice
储存温度
−20°C
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一般描述
Contains ≤500 ppm impurities by GC, including trace monomer and residual organics.
应用
Biocompatible block copolymer. Can be used in the formation of nanoparticles for drug delivery. Potential use in the targeted and/or controlled release of cancer drugs, anti-inflammatory drugs, antibiotics, or anesthetic agents.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Tumour-associated macrophages act as a slow-release reservoir of nano-therapeutic Pt(IV) pro-drug.
Miller MA, et al.
Nature Communications, 6 (2015)
Paclitaxel-loaded PEGylated PLGA-based nanoparticles: In vitro and in vivo evaluation.
Danhier F, et al.
J. Controlled Release, 133, 11-17 (2009)
Yihan Xu et al.
Journal of biomedical materials research. Part B, Applied biomaterials, 105(6), 1692-1716 (2016-04-22)
Poly (lactic-co-glycolic acid) (PLGA) copolymers have been broadly used in controlled drug release applications. Because these polymers are biodegradable, they provide an attractive option for drug delivery vehicles. There are a variety of material, processing, and physiological factors that impact
R Gref et al.
Science (New York, N.Y.), 263(5153), 1600-1603 (1994-03-18)
Injectable nanoparticulate carriers have important potential applications such as site-specific drug delivery or medical imaging. Conventional carriers, however, cannot generally be used because they are eliminated by the reticulo-endothelial system within seconds or minutes after intravenous injection. To address these
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