804568

(R,S)-Bode Kinetic Resolution Catalyst

• 别名: (4aR,9aS)-6-Bromo-4-hydroxy-4,4a,9,9a-tetrahydroindeno[2,1-b][1,4]oxazin-3(2H)-one
• 经验公式（希尔记法）: C₁₁H₁₀BrNO₃
• CAS号: 1394957-71-1
• 分子量: 284.11
• MDL编号: MFCD29037020
• UNSPSC代码: 12352101
• PubChem化学物质编号: 329768882
• NACRES: NA.22

属性

• 表单: solution
• 质量水平: 100
• 官能团: bromo; ether
• 储存温度: 15-25°C
• SMILES字符串: O=C(CO1)N(O)[C@@]2([H])[C@]1([H])CC3=CC=C(Br)C=C32
• InChI: 1S/C11H10BrNO3/c12-7-2-1-6-3-9-11(8(6)4-7)13(15)10(14)5-16-9/h1-2,4,9,11,15H,3,5H2/t9-,11+/m0/s1
• InChI key: FQXSUQCCAHKURK-GXSJLCMTSA-N

说明

应用

The following hydroxamic acid catalyst was shown by Bode and coworkers to assist in the kinetic resolution of cyclic amines through acylation of one enantiomer, which can be controlled using either the (R or S)- or (S or R)-Bode Kinetic Resolution Catalyst, both of which are also available through Sigma-Aldrich.
It can also be employed in the preparation of nonracemic piperidines by kinetic resolution using an α-hydroxy-α′, β-unsaturated ketone in the presence of a pyrrolotriazolium salt.

其他说明

Expanded substrate scope and catalyst optimization for the catalytic kinetic resolution of N-heterocycles

安全信息

• 象形图: GHS07
• 警示用语：: Warning
• 危险声明: H302
• 预防措施声明: P301 + P312 + P330
• 危险分类: Acute Tox. 4 Oral
• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 3
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable