表单
solid
分子量
average Mn 5,000
PDI
≤2.5
储存温度
2-8°C
一般描述
Poly(N-isopropylacryamide) (PNIPAAm) is a thermoresponsive polymer. It is soluble in water below its lower critical solution temperature (LCST) (32°C) whereas it forms intramolecular hydrogen bonds thus becoming insoluble at temperatures above its LCST. PNIPAAm is functionalized with a silane coupling agent like triethoxysilane in order to reduce its surface energy thus making it hydrophobic. Triethoxysilane terminated PNIPAAm thus exhibits a switchable superhydrophobic/hydrophilic surface and are widely used as hydrophobic valves in microfluidic channels.
应用
- Used in the synthesis of microspheres which are used in drug-delivery systems.
- Used in fluidic devices, in protein affinity separation, and as cell culture substrates.
特点和优势
It exhibits swelling or deswelling behaviour with respect to external temperature which favours in nucleic acid adsorption and drug release applications.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Conformal switchable superhydrophobic/hydrophilic surfaces for microscale flow control.
Chunder, A., Etcheverry, K., Londe, G., Cho, H. J., & Zhai, L.
Colloids and Surfaces. A, Physicochemical and Engineering Aspects, 333(1), 187-193 (2009)
Qiang He et al.
Langmuir : the ACS journal of surfaces and colloids, 23(7), 3981-3987 (2007-02-24)
Micro- and nanopatterns of thermosensitive poly(N-isopropylacrylamide) brush on gold substrate were prepared by using chemical lithography combined with surface-initiated atom transfer radical polymerization. Self-assembled monolayers of 4'-nitro-1, 1'-biphenyl-4-thiol were structured by chemical lithography which produced cross-linked 4'-amino-1,1'-biphenyl-4-thiol monolayer within a
Poly (N-isopropylacrylamide)-coated luminescent/magnetic silica microspheres: preparation, characterization, and biomedical applications
Guo, J., Yang, W., Wang, C., He, J., & Chen, J.
Chemistry of Materials, 18(23), 5554-5562 (2006)
商品
By altering the physicochemical properties, smart or intelligent drug delivery systems can be designed to deliver therapeutic molecules on-demand. Learn more about the application of stimuli-responsive materials in drug delivery.
通过调整的理化特性，药物递送系统可根据需要设计为可递送治疗分子的智能系统。了解有关刺激响应材料药物递送应用的更多信息。
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