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Merck

690198

Sigma-Aldrich

3,4-二乙氧基-3-环丁烯-1,2-二酮

Lonza quality, ≥98.0% (GC)

别名:

四方酸二乙酯, 方酸二乙酯

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About This Item

线性分子式:
(C2H5O)2C4(=O)2
CAS号:
分子量:
170.16
Beilstein:
640626
MDL號碼:
分類程式碼代碼:
12352100

等級

Lonza quality

化驗

≥98.0% (GC)

製造商/商標名

Lonza Ltd

折射率

n20/D 1.509 (lit.)

bp

95 °C/0.1 mmHg (lit.)

密度

1.15 g/mL at 25 °C (lit.)

SMILES 字串

CCOC1=C(OCC)C(=O)C1=O

InChI

1S/C8H10O4/c1-3-11-7-5(9)6(10)8(7)12-4-2/h3-4H2,1-2H3

InChI 密鑰

DFSFLZCLKYZYRD-UHFFFAOYSA-N

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象形圖

Health hazardExclamation mark

訊號詞

Danger

危險分類

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

230.0 °F - closed cup

閃點(°C)

110 °C - closed cup

個人防護裝備

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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分析证书(COA)

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E F Sherertz et al.
Archives of dermatological research, 280(1), 57-60 (1988-01-01)
Squaric acid diethylester and squaric acid dibutylester have been used in contact sensitization therapy of alopecia areata. This study investigated the application of these esters or squaric acid alone to hairless mouse and human skin in vitro to determine squaric
Frederik Wurm et al.
Biomacromolecules, 13(4), 1161-1171 (2012-03-02)
Polymer-protein conjugates generated from side chain functional synthetic polymers are attractive because they can be easily further modified with, for example, labeling groups or targeting ligands. The residue specific modification of proteins with side chain functional synthetic polymers using the
L F Tietze et al.
Bioconjugate chemistry, 2(3), 148-153 (1991-05-01)
The coupling of p-aminophenyl 2-acetamido-2-deoxy-3-O-beta-D- galactopyranosyl-beta-D-galactopyranoside (gal-beta 1,3-galNAc) to bovine serum albumin (BSA) was achieved by using 1,2-diethoxycyclobutene-3,4-dione (squaric acid diester) as a new coupling reagent. Two selective consequential steps afforded the desired neoglycoprotein: reaction of the p-aminophenyl group of
M G Wilkerson et al.
Journal of the American Academy of Dermatology, 13(2 Pt 1), 229-234 (1985-08-01)
Two squaric acid diesters, squaric acid diethyl ester (SADEE) and squaric acid dibutyl ester (SADBE), have been suggested as replacements for 2,4-dinitrochlorobenzene in the treatment of alopecia areata and alopecia totalis. We synthesized these squaric acid diesters and examined them
Sensitizing potential of cyclobutenediones.
J Avalos et al.
Contact dermatitis, 21(5), 341-342 (1989-11-01)

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