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质量水平
方案
97%
表单
solid
mp
310 °C (lit.)
官能团
carboxylic acid
SMILES字符串
OC(=O)c1ccc(OCCCOc2ccc(cc2)C(O)=O)cc1
InChI
1S/C17H16O6/c18-16(19)12-2-6-14(7-3-12)22-10-1-11-23-15-8-4-13(5-9-15)17(20)21/h2-9H,1,10-11H2,(H,18,19)(H,20,21)
InChI key
VBISQLWPGDULSX-UHFFFAOYSA-N
应用
用于聚酐(一类应用于多种给药系统的生物可蚀性聚合物)的结构单元。
警示用语:
Warning
危险声明
危险分类
Aquatic Acute 1 - Skin Sens. 1
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Moon Suk Kim et al.
Bio-medical materials and engineering, 15(3), 229-238 (2005-05-25)
p-Carboxyphenoxy propane (CPP) prepolymer consisting of 4 units and sebacic acid (SA) prepolymer consisting of about 10 units were synthesized by reacting CPP and SA in the presence of excess acetic anhydride, respectively. Polyanhydride, poly(CPP-SA) copolymers were copolymerized by a
Sijian Hou et al.
Macromolecular bioscience, 7(5), 620-628 (2007-04-26)
To tailor the erosion rate of polyanhydrides while retaining their surface erosion characteristics, new three-component polyanhydrides of sebacic acid, 1,3-bis(p-carboxyphenoxy)propane and poly(ethylene glycol) were synthesized. The hydrophilicity of the polymer increased and its mechanical strength decreased with increasing PEG content.
A D'Emanuele et al.
Pharmaceutical research, 9(10), 1279-1283 (1992-10-01)
We report a study of the effects of polymer molecular weight on the erosion of polyanhydride copolymer matrices composed of 1,3-bis(p-carboxyphenoxy)-propane (CPP) and sebacic acid (SA) in aqueous solution. The erosion profile characteristically displays an induction period during which the
A J Domb et al.
Biomaterials, 15(9), 681-688 (1994-07-01)
The metabolic disposition and elimination process of the anhydride co-polymer poly[1,3-bis(p-carboxy-phenoxypropane):sebacic acid] 20:80 [P(CPP:Sa)20:80] implanted in the rat brain was studied. Two polymers were prepared, one with [14C]SA and unlabelled CPP, and the other co-polymer with [14C]CPP and unlabelled SA.
Xiaohua Liu et al.
Biomaterials, 28(28), 4124-4131 (2007-06-20)
Intermittent (pulsatile) administration of parathyroid hormone (PTH) is known to improve bone micro-architecture, mineral density and strength. Therefore, daily injection of PTH has been clinically used for the treatment of osteoporosis. However, this regimen of administration is not convenient and
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