544639

甲磺酰乙酮

97%

• 别名: 1-(Methylsulfonyl)-2-propanone, NSC 35395
• 线性分子式: CH₃C(O)CH₂SO₂CH₃
• CAS号: 5000-46-4
• 分子量: 136.17
• EC號碼: 225-665-6
• MDL號碼: MFCD00014745
• 分類程式碼代碼: 12352100
• PubChem物質ID: 24878779
• NACRES: NA.22

属性

• 化驗: 97%
• 形狀: powder or crystals
• mp: 48-52 °C (lit.)
• SMILES 字串: CC(=O)CS(C)(=O)=O
• InChI: 1S/C4H8O3S/c1-4(5)3-8(2,6)7/h3H2,1-2H3
• InChI 密鑰: NWEYGXQKFVGUFR-UHFFFAOYSA-N

说明

一般說明

Methanesulfonylacetone is a sulfonyl group-containing active methylene compound. It can react with Baylis–Hillman acetates in dimethylformamide/potassium carbonate system to form ortho-hydroxyacetophenone derivatives.

應用

Methanesulfonylacetone may be used in the preparation of 6-bromo-3-methanesulfonyl-2-methyl-quinolin-4-ol.

Reactant for:

• Stereoselective preparation of chiral cyclic ketones
• Preparation of poly-substituted pyridines
• Multicomponent cyclocondensation with aldehydes and aminoazoles
• Gold-catalyzed Friedlander cyclocondensation reaction
• Radical homoallylation reactions

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, type N95 (US)