所有图片(1)
About This Item
经验公式（希尔记法）:
C10H16N2O2
CAS号:
分子量:
196.25
MDL號碼:
分類程式碼代碼:
12352005
PubChem物質ID:
NACRES:
NA.22
推荐产品
化驗
97%
光學活性
[α]20/D −105.5°, c = 1 in chloroform
mp
33-36 °C (lit.)
SMILES 字串
CC(C)(C)OC(=O)N1CCC[C@H]1C#N
InChI
1S/C10H16N2O2/c1-10(2,3)14-9(13)12-6-4-5-8(12)7-11/h8H,4-6H2,1-3H3/t8-/m0/s1
InChI 密鑰
MDMSZBHMBCNYNO-QMMMGPOBSA-N
應用
用于合成脯氨酰寡肽酶抑制剂。
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 3
閃點（°F）
230.0 °F - closed cup
閃點（°C）
110 °C - closed cup
個人防護裝備
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Janice Lawandi et al.
Journal of medicinal chemistry, 52(21), 6672-6684 (2009-11-06)
Prolyl oligopeptidases cleave peptides on the carboxy side of internal proline residues and their inhibition has potential in the treatment of human brain disorders. Using our docking program fitted, we have designed a series of constrained covalent inhibitors, built from
Erik A A Wallén et al.
Journal of medicinal chemistry, 46(21), 4543-4551 (2003-10-03)
Isophthalic acid bis(l-prolyl-pyrrolidine) amide is a very potent prolyl oligopeptidase inhibitor, but it has a log P value of -0.2, which is very low for a compound targeted to the brain. Therefore, these types of compounds were further modified to
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门