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Merck

534579

Sigma-Aldrich

(R)-(-)-2-氨基-1-戊醇

97%

别名:

D-戊氨醇

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About This Item

线性分子式:
CH3(CH2)2CH(NH2)CH2OH
CAS号:
分子量:
103.16
MDL號碼:
分類程式碼代碼:
12352116
PubChem物質ID:
NACRES:
NA.22

化驗

97%

光學活性

[α]20/D −17°, c = 1 in chloroform

mp

44-48 °C (lit.)

SMILES 字串

CCC[C@@H](N)CO

InChI

1S/C5H13NO/c1-2-3-5(6)4-7/h5,7H,2-4,6H2,1H3/t5-/m1/s1

InChI 密鑰

ULAXUFGARZZKTK-RXMQYKEDSA-N

應用

(R)-(-)-2-Amino-1-pentanol can be used as a chiral building block to prepare:
  • A key intermediate, (R)-N-(p-toluenesulfonyl)-2-propylaziridine, which is utilized in the total synthesis of (R)-1-(benzofuran-2-yl)-2-propylaminopentane.
  • (R)-N-benzyloxycarbonyl-aminoaldehydes as potential substrates for dihydroxyacetone phosphate (DHAP)-dependent aldolases.
  • (R)-2-((2-Aminoquinazolin-4-yl)amino)pentan-1-ol as a potent dual toll-like receptor and modulator.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

204.8 °F - closed cup

閃點(°C)

96 °C - closed cup

個人防護裝備

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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2, 4-diaminoquinazolines as dual toll-like receptor (TLR) 7/8 modulators for the treatment of hepatitis B virus
Embrechts W, et al.
Journal of Medicinal Chemistry, 61(14), 6236-6246 (2018)
Enantioselective synthesis and absolute configuration of (-)-1-(benzofuran-2-yl)-2-propylaminopentane,((-)-BPAP), a highly potent and selective catecholaminergic activity enhancer
Oka T, et al.
Bioorganic & Medicinal Chemistry, 9(5), 1213-1219 (2001)
Dihydroxyacetone phosphate aldolase catalyzed synthesis of structurally diverse polyhydroxylated pyrrolidine derivatives and evaluation of their glycosidase inhibitory properties
Calveras J, et al.
Chemistry?A European Journal , 15(30), 7310-7328 (2009)

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