所有图片(1)
About This Item
经验公式（希尔记法）:
C6H7NO
CAS号:
分子量:
109.13
MDL號碼:
分類程式碼代碼:
12352005
PubChem物質ID:
NACRES:
NA.22
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品質等級
化驗
≥98%
光學活性
[α]20/D +565°, c = 1 in chloroform
光學純度
ee: 99% (HPLC)
mp
94-97 °C (lit.)
SMILES 字串
O=C1N[C@H]2C[C@@H]1C=C2
InChI
1S/C6H7NO/c8-6-4-1-2-5(3-4)7-6/h1-2,4-5H,3H2,(H,7,8)/t4-,5+/m0/s1
InChI 密鑰
DDUFYKNOXPZZIW-CRCLSJGQSA-N
應用
这种内酰胺及其对映体是碳环核苷卡波韦对映异构体的前体。已证实 (-)-卡波韦是一种 HIV-1 强效抑制剂，根据临床试验可作为 AZT 的备选药。AZT 是 Wellcome Foundation Ltd. 的商标
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
E L White et al.
Biochemical and biophysical research communications, 161(2), 393-398 (1989-06-15)
Carbocylic 2',3'-didehydro-2',3'-dideoxyguanosine (Carbovir; NSC 614846) is an antiretroviral agent which may be useful in the treatment of AIDS. We have synthesized the 5'-triphosphate of Carbovir and examined its ability to inhibit human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (EC
Jung. M.E. Rhee, H.
The Journal of Organic Chemistry, 59, 4719-4719 (1994)
Evans, C.T. et al.
Journal of the Chemical Society. Perkin Transactions 1, 589-589 (1992)
Handa, S. et al.
Journal of the Chemical Society. Perkin Transactions 1, 1885-1885 (1994)
Campbell, J.A. et al.
The Journal of Organic Chemistry, 60, 4602-4602 (1995)
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