407135

(1R,2S)-(+)-2-(二丁氨基)-1-苯基-1-丙醇

97%

• 别名: (+)-DBNE, N,N-二丁基-L-(+)-去甲麻黄素
• 线性分子式: [CH₃(CH₂)₃]₂NCH(CH₃)CH(C₆H₅)OH
• CAS号: 115651-77-9
• 分子量: 263.42
• MDL號碼: MFCD00142689
• 分類程式碼代碼: 12352116
• PubChem物質ID: 24865427

属性

• 化驗: 97%
• 光學活性: [α]20/D +21°, c = 2 in chloroform
• 折射率: n20/D 1.501 (lit.)
• bp: 121 °C/0.1 mmHg (lit.)
• 密度: 0.94 g/mL at 25 °C (lit.)
• SMILES 字串: CCCCN(CCCC)[C@@H](C)[C@H](O)c1ccccc1
• InChI: 1S/C17H29NO/c1-4-6-13-18(14-7-5-2)15(3)17(19)16-11-9-8-10-12-16/h8-12,15,17,19H,4-7,13-14H2,1-3H3/t15-,17-/m0/s1
• InChI 密鑰: BRRGNOFUBFINSX-RDJZCZTQSA-N

说明

一般說明

(1R,2S)-(+)-2-(Dibutylamino)-1-phenyl-1-propanol, a norephedrine derivative, is a chiral auxiliary for asymmetric synthesis.

應用

(+)-DBNE reacts with nickel bromide (NiBr₂) to form a chiral catalyst, which can catalyze the enantioselective conjugate addition of dialkylzincs to α,β-unsaturated ketones leading to the formation of optically active β-substituted ketones.

安全信息

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H315,H319,H335
• 防範說明: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危險分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: 230.0 °F - closed cup
• 閃點（°C）: 110 °C - closed cup
• 個人防護裝備: Eyeshields, Gloves, type ABEK (EN14387) respirator filter