392731

(DHQD)₂PHAL

≥95%

• 别名: 氢化奎尼定 1,4-(2,3-二氮杂萘)二醚
• 经验公式（希尔记法）: C₄₈H₅₄N₆O₄
• CAS号: 140853-10-7
• 分子量: 778.98
• Beilstein: 5475678
• MDL號碼: MFCD00198107
• 分類程式碼代碼: 12352005
• PubChem物質ID: 24864481
• NACRES: NA.22

属性

• 化驗: ≥95%
• 形狀: powder
• 光學活性: [α]22/D −262°, c = 1.2 in methanol
• 環保替代產品評分: old score: 5; new score: 3; Find out more about DOZN™ Scoring
• 環保替代產品特色: Waste Prevention; Less Hazardous Chemical Syntheses; Safer Solvents and Auxiliaries; Inherently Safer Chemistry for Accident Prevention; Learn more about the Principles of Green Chemistry.
• sustainability: Greener Alternative Product
• mp: 160 °C (dec.) (lit.)
• 環保替代類別: , Re-engineered
• SMILES 字串: CC[C@H]1CN2CCC1CC2[C@@H](Oc3nnc(O[C@H](C4CC5CCN4C[C@@H]5CC)c6ccnc7ccc(OC)cc67)c8ccccc38)c9ccnc%10ccc(OC)cc9%10
• InChI: 1S/C48H54N6O4/c1-5-29-27-53-21-17-31(29)23-43(53)45(35-15-19-49-41-13-11-33(55-3)25-39(35)41)57-47-37-9-7-8-10-38(37)48(52-51-47)58-46(44-24-32-18-22-54(44)28-30(32)6-2)36-16-20-50-42-14-12-34(56-4)26-40(36)42/h7-16,19-20,25-26,29-32,43-46H,5-6,17-18,21-24,27-28H2,1-4H3/t29-,30-,31-,32-,43+,44+,45-,46-/m0/s1
• InChI 密鑰: YUCBLVFHJWOYDN-HVLQGHBFSA-N

说明

一般說明

(DHQD)₂PHAL is a dimer that can be used as a chiral amine catalyst for asymmetric halogenations.

(DHQD)₂PHAL is a modified cinchona alkaloid derivative mainly used as a ligand for enantioselective catalysis.

We are committed to bringing you Greener Alternative Products, which adhere to one of the four categories of Greener Alternatives . This product belongs to category of Re-engineered products, showing key improvements in Green Chemistry Principles “Waste Prevention”, “Less Hazardous Chemical Syntheses”, "Safer Solvents and Auxiliaries" and “Inherently Safer Chemistry for Accident Prevention”. Click here to view its DOZN scorecard.

應用

(DHQD)₂PHAL may be used as ligand for:

• Osmium trioxide catalyzed asymmetric dihydroxylation of olefins.
• Palladium catalyzed Suzuki-Miyaura coupling of aryl/heteroaryl halides with aryl boronic acids in aqueous medium and in the absence of phosphine/organic solvent.
• Copper(I)-catalyzed azide-alkyne cycloaddition reaction to synthesize 1,2,3-triazoles in water.

Hydroquinidine 1,4-phthalazinediyl diether [(DHQD)₂PHAL] can be used:

• As a ligand for Sharpless asymmetric dihydroxylation.
• For enantioselective α-fluorination of carbonyl compounds.

法律資訊

经 Rhodia Pharma Solutions 授权销售。

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, type N95 (US)