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Merck

365572

Sigma-Aldrich

6-甲氧基-2-吲哚羧酸甲酯

99%

别名:

2-Methoxycarbonyl-6-methoxyindole, 6-Methoxyindole-2-carboxylic acid methyl ester

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About This Item

经验公式(希尔记法):
C11H11NO3
CAS号:
分子量:
205.21
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

化驗

99%

mp

117-119 °C (lit.)

官能基

ester

SMILES 字串

COC(=O)c1cc2ccc(OC)cc2[nH]1

InChI

1S/C11H11NO3/c1-14-8-4-3-7-5-10(11(13)15-2)12-9(7)6-8/h3-6,12H,1-2H3

InChI 密鑰

OPUUCOLVBDQWEY-UHFFFAOYSA-N

應用

Methyl 6-methoxy-2-indolecarboxylate is suitable for use in the production of dyes by Escherichia coli expressing naphthalene dioxygenase (NDO) and toluene dioxygenase (TDO). It is also suitable for use in the production of dyes by Escherichia coli expressing multicomponent phenol hydroxylase (mPH) from Pseudomonas sp. strains KL33 and KL28.
Reactant for preparation of:
  • Benzoxazole containing indole analogs as peroxisome proliferator-activated receptor-γ/δ dual agonists
  • Potent antiproliferative agent against human leukemia K562 cells
  • Indole-indolone scaffold via [3+2] annulation of arynes
  • Latonduine derivatives via intramolecular Heck reaction as possible anticancer agents
  • Arylthioindoles as potent inhibitors of tubulin polymerization
  • Heterocycle-fused derivatives of 1-oxo-1,2,3,4-tetrahydropyrazine via Ugi condensation
  • Indole fatty alcohols (IFAs) as promoters of differentiation of neural stem cell derived neurospheres into neurons. Potential application for treatment of neurodegenerative diseases
  • Light-dependent tumor necrosis factor-α antagonists
  • 2-substituted indole melatonin receptor ligands

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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J Y Kim et al.
Letters in applied microbiology, 36(6), 343-348 (2003-05-20)
To isolate and characterize the phorate [O,O-diethyl-S-(ethylthio)methyl phosphoradiothioate] degrading bacteria from agricultural soil, and their assessment for multifarious biological activities of environmental and agronomic significance. Based on their morphological and biochemical characteristics, the selected isolates PS-1, PS-2 and PS-3 were
J Y Kim et al.
Letters in applied microbiology, 41(2), 163-168 (2005-07-22)
To establish multicomponent phenol hydroxylases (mPHs) as novel biocatalysts for producing dyestuffs and hydroxyindoles such as 7-hydroxyindole (7-HI) from indole and its derivatives. We have isolated Pseudomonas sp. KL33, which possesses a phenol degradation pathway similar to that found in

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