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化驗
98%
形狀
powder
mp
125-128 °C (lit.)
SMILES 字串
Cn1nnnc1S
InChI
1S/C2H4N4S/c1-6-2(7)3-4-5-6/h1H3,(H,3,5,7)
InChI 密鑰
XOHZHMUQBFJTNH-UHFFFAOYSA-N
一般說明
5-巯基-1-甲基四唑是一种杂环硫醇衍生物。它可与三甲基镓形成二聚体或四聚体复合物。
應用
5-巯基-1-甲基四唑可用作杂环配体,以研究半配位和全配位铅(II)络合物中铅原子上孤对电子的几何形状和立体化学活性。它可用于中孔MSU-2二氧化硅 和SBA-15中孔二氧化硅的亚微米颗粒的化学改性。
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
4.1A - Other explosive hazardous materials
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
Journal of pharmaceutical and biomedical analysis, 8(1), 73-77 (1990-01-01)
A simple, fast and sensitive method for the quantitative determination of 1-methyl-1H-tetrazole-5-thiol using HPLC is reported. Samples are deproteinated by plasma water filtration and injected into a HPLC system capable of column switching and backflushing the analytical column. The limit
Japanese journal of pharmacology, 45(3), 303-315 (1987-11-01)
The disulfiram-like effect of various beta-lactam antibiotics containing N-methyltetrazolethiol (NMTT) on the alcohol-metabolizing system was studied using rats. Their administration caused decreased activities in low Km aldehyde dehydrogenase (ALDH) and acetaldehyde oxidation in the liver, with marked depression from several
Journal of hazardous materials, 166(2-3), 1449-1458 (2009-01-23)
A SBA-15 mesoporous silica has been chemically modified with 5-mercapto-1-methyltetrazole. The newly synthesized material (MTTZ-SBA-15) has been characterized, by powder X-ray diffraction, N(2) adsorption, FT-IR, (13)C NMR spectroscopy and elemental analysis, and used to preconcentrate Zn(II) in water samples. The
Antimicrobial agents and chemotherapy, 33(6), 857-861 (1989-06-01)
The N-methylthiotetrazole side chain (NMTT) that is present on several cephalosporins has been implicated in the development of antibiotic-associated hypoprothrombinemia. A randomized three-way crossover trial was conducted to compare the release of the NMTT side chain from three NMTT-containing antibiotics.
Drug metabolism and drug interactions, 7(2-3), 149-160 (1989-01-01)
The effect of biliary diversion on the ability of cefamandole, a methyltetrazole-thiol (MTT) containing antibiotic, to alter both hepatic vitamin K metabolism and the gamma-carboxylation of glutamic acid were examined in the rat, in order to understand the hypoprothrombinemia associated
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