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Merck

309346

Sigma-Aldrich

L-谷氨酸二乙酯 盐酸盐

97%

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About This Item

线性分子式:
C2H5OCOCH2CH2CH(NH2)COOC2H5 · HCl
CAS号:
分子量:
239.70
Beilstein:
3597595
EC 号:
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.22

质量水平

方案

97%

旋光性

[α]18/D +22°, c = 1 in H2O

反应适用性

reaction type: solution phase peptide synthesis

mp

108-110 °C (lit.)

应用

peptide synthesis

SMILES字符串

Cl[H].CCOC(=O)CC[C@H](N)C(=O)OCC

InChI

1S/C9H17NO4.ClH/c1-3-13-8(11)6-5-7(10)9(12)14-4-2;/h7H,3-6,10H2,1-2H3;1H/t7-;/m0./s1

InChI key

WSEQLMQNPBNMSL-FJXQXJEOSA-N

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应用

L-Glutamic acid diethyl ester hydrochloride can be used in the synthesis of:
  • Oligo(γ-ethyl L-glutamate) via oligomerization catalyzed by papain.
  • L-glutamic acid based dendritic compounds.
  • Poly(α-peptide) by polymerization and copolymerization in the presence of protease catalysts.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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F Barnabi et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 281(5), R1665-R1674 (2001-10-20)
Neurotransmitters relaying ascending visceral information were examined by comparing the response of neurons in the insular cortex to vagal stimulation (0.8 Hz, 2 mA) before and after neurotransmitter antagonist injections (200 nl) in the ventroposterior parvocellular nucleus of the thalamus
P D Evans et al.
The Journal of experimental biology, 173, 229-249 (1992-12-01)
L-Glutamate application can produce three different responses in the membrane potential of the Schwann cell of the tropical squid, Sepioteuthis sepioidea, which appear to be mediated by three pharmacologically distinct classes of receptor. A class of non-NMDA-type receptors, with some
B W Peeters et al.
Brain research bulletin, 33(6), 715-718 (1994-01-01)
The interaction between NMDA and nonNMDA receptors was studied in nonconvulsive epilepsy in WAG/Rij rats. Compounds acting on NMDA (NMDA, APH) and nonNMDA (AMPA, GDEE, kainic acid, kynurenic acid) receptors were coinjected intracerebroventricularly. The WAG/Rij rat strain may be an
Asako Narai-Kanayama et al.
Biochimica et biophysica acta, 1780(6), 881-891 (2008-04-15)
Papain polymerizes L-glutamic acid diethyl ester (Glu-di-OEt) regioselectively, resulting in the formation of poly (gamma-ethyl alpha-L-glutamic acid) with various degrees of polymerization of less than 13. Reaction temperatures below 20 degrees C were appropriate for the reaction in terms of
Ultrasound induced formation of organogel from a glutamic dendron
Li Y, et al.
Tetrahedron, 63(31), 7468-7473 (2007)

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