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Merck

301450

Sigma-Aldrich

4-溴甲基-6,7-二甲氧基香豆素

96%

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About This Item

经验公式(希尔记法):
C12H11BrO4
CAS号:
分子量:
299.12
Beilstein:
4750487
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

96%

mp

212-216 °C (lit.)

螢光

λex 322; λem 395 (Reaction product with acetic acid)
λex 354 nm; λem 435 nm in methanol

官能基

bromo
ester

SMILES 字串

COc1cc2OC(=O)C=C(CBr)c2cc1OC

InChI

1S/C12H11BrO4/c1-15-10-4-8-7(6-13)3-12(14)17-9(8)5-11(10)16-2/h3-5H,6H2,1-2H3

InChI 密鑰

JGODLBJJCNQFII-UHFFFAOYSA-N

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應用

荧光标记试剂,用于羧酸的反相 HPLC 分离和检测。

象形圖

Exclamation mark

訊號詞

Warning

危險分類

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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A P Starling et al.
The Biochemical journal, 304 ( Pt 2), 569-575 (1994-12-01)
On reconstitution of the Ca(2+)-ATPase of skeletal muscle sarcoplasmic reticulum into bilayers of dimyristoleoylphosphatidylcholine [di(C14:1)PC] or dinervonylphosphatidylcholine [di(C24:1)PC] the stoichiometry of Ca2+ binding changes from the usual two Ca2+ ions bound per ATPase molecule to one Ca2+ ion bound per
H I Stefanova et al.
Biochemistry, 31(26), 6023-6031 (1992-07-07)
The (Ca(2+)-Mg2+)-ATPase of sarcoplasmic reticulum was labeled with 4-(bromomethyl)-6,7-dimethoxycoumarin. It was shown that a single cysteine residue (Cys-344) was labeled on the ATPase, with a 25% reduction in steady-state ATPase activity and no reduction in the steady-state rate of hydrolysis
K A Dalton et al.
The Biochemical journal, 329 ( Pt 3), 637-646 (1998-03-07)
The sarcoplasmic reticulum of skeletal muscle contains anionic phospholipids as well as the zwitterionic phosphatidylcholine and phosphatidylethanolamine. Here we study the effects of anionic phospholipids on the activity of the Ca2+-ATPase purified from the membrane. Reconstitution of the Ca2+-ATPase into
4-Bromomethyl-6,7-dimethoxycoumarin as a fluorescence reagent for precolumn derivatization of 5-fluorouracil compounds in high-performance liquid chromatography.
S Yoshida et al.
Journal of chromatography, 430(1), 156-162 (1988-08-19)
Determination of 3-deazaguanine in mice plasma by high-performance liquid chromatography.
B Chandrasekaran et al.
Journal of chromatography, 309(2), 403-408 (1984-08-10)

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