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Merck

23100

Sigma-Aldrich

氯醛 水合物

crystallized, ≥98.0% (T)

别名:

三氯乙醛 水合物

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About This Item

线性分子式:
Cl3CCH(OH)2
CAS号:
分子量:
165.40
Beilstein:
1698497
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

化驗

≥98.0% (T)

形狀

solid

品質

crystallized

mp

57 °C (lit.)

SMILES 字串

OC(O)C(Cl)(Cl)Cl

InChI

1S/C2H3Cl3O2/c3-2(4,5)1(6)7/h1,6-7H

InChI 密鑰

RNFNDJAIBTYOQL-UHFFFAOYSA-N

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應用

水合氯醛可用作:
  • 与手性亚胺反应,不对称合成 β-三氯甲基-β-羟基酮的反应物
  • 用于在有机溶剂中有效脱保护缩醛、二硫代缩醛和四氢吡喃基醚的水载体
  • 在盐酸、硫酸钠和盐酸羟胺存在下,用 2-碘苯胺合成 2-(羟基亚氨基)-N-(2-碘苯基)乙酰胺的反应物

其他說明

可能实行销售限制

象形圖

Skull and crossbones

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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Jianguo Wang et al.
Journal of agricultural and food chemistry, 59(18), 9892-9900 (2011-08-16)
Acetohydroxyacid synthase (AHAS) catalyzes the first common step in the biosynthesis of the branched-chain amino acids. As a result of its metabolic importance in plants, it is a target for many commercial herbicides. Virtual screening analysis inspired the evaluation of
Chloral hydrate as a water carrier for the efficient deprotection of acetals, dithioacetals, and tetrahydropyranyl ethers in organic solvents
Chandrasekhar S, et al.
Synthetic Communications, 44, 1904-1913 (2014)
Kazumasa Funabiki et al.
Organic letters, 5(12), 2059-2061 (2003-06-07)
[reaction: see text] Chloral or its hydrate undergoes the carbon-carbon bond-formation reaction with various optically active imines in the absence of any additive, followed by hydrolysis, to produce the corresponding beta-trichloromethyl-beta-hydroxy ketones in good yields with high enantioselectivities. In addition
Litong Fan et al.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 37(6), 1387-1397 (2019-01-16)
Transforming growth factor beta (TGF-β) is commonly utilized in chondrogenic differentiation protocols, but this often results in incomplete maturation of the derived chondrocytes. Gene expression analysis, quantitation of sulfated glycosaminoglycan and collagen, and histological staining were performed to assess the
Simone Jürschik et al.
Journal of mass spectrometry : JMS, 47(9), 1092-1097 (2012-09-14)
In this work, we illustrate the application of proton transfer reaction mass spectrometry (PTR-MS) in the field of food and drink safety. We present proof-of-principle measurements of four different drinks (water, tea, red wine and white wine) each spiked separately

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