化驗
97%
SMILES 字串
ClC(Cl)C(=O)NCCCCCCCCNC(=O)C(Cl)Cl
訊號詞
Warning
危險聲明
危險分類
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Carc. 2
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
K Momma et al.
Fetal diagnosis and therapy, 9(1), 44-52 (1994-01-01)
Interrupted aortic arch type B associated with ventricular septal defect (n = 17) or atrioventricular septal defect (n = 2) was induced in 19 of 300 fetuses by maternal administration of bis-diamine on the 9th and 10th day of pregnancy.
John K Amory et al.
Journal of andrology, 32(1), 111-119 (2010-08-14)
The bisdichloroacetyldiamine WIN 18,446 reversibly inhibits spermatogenesis in many species, including humans; however, the mechanism by which WIN 18,446 functions is unknown. As retinoic acid is essential for spermatogenesis, we hypothesized that WIN 18,446 might inhibit retinoic acid biosynthesis from
H Tasaka et al.
Teratology, 43(3), 191-200 (1991-03-01)
Administration of N,N'-bis(dichloroacetyl)-1,8-octamethylenediamine, bisdiamine, in pregnant Donryu rats on day 10 of gestation induces a high incidence of cardiovascular anomalies in fetuses. Bisdiamine administration induced aplasia of the sixth aortic arch artery, with both the right and left primitive pulmonary
Takashi Hanato et al.
Birth defects research. Part B, Developmental and reproductive toxicology, 92(1), 10-16 (2011-02-12)
Conotruncal anomalies are often associated with abnormal coronary arteries. Although bis-diamine is known to induce conotruncal defects, its pathological effects on coronary vascular development have not been demonstrated. This study sought to assess the teratogenic effects of bis-diamine on coronary
Cathryn A Hogarth et al.
Biology of reproduction, 88(2), 40-40 (2013-01-04)
The BDADs (bis-[dichloroacetyl]-diamines) are compounds that can inhibit spermatogenesis via blocking the metabolism of vitamin A. We utilized one specific BDAD, WIN 18,446, to manipulate the endogenous production of retinoic acid (RA) in the testis to further investigate the action
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