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化驗
97%
mp
163-165 °C (lit.)
SMILES 字串
Oc1ccc(Cl)cn1
InChI
1S/C5H4ClNO/c6-4-1-2-5(8)7-3-4/h1-3H,(H,7,8)
InChI 密鑰
SZFUWUOHDRMCKD-UHFFFAOYSA-N
一般說明
5-氯-2-羟基吡啶作为供体配体,以两性离子形式存在,即 5-氯吡啶-2-酸酯存在于铜配合物中 。
應用
用 5-氯-2-羟基吡啶 (5-chloro-2-pyridinol) 研究双香豆素对黄嘌呤脱氢酶的影响 及黄嘌呤脱氢酶还原丝裂霉素 C 的机理 。
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
其他客户在看
Acta crystallographica. Section C, Crystal structure communications, 58(Pt 4), M270-M272 (2002-04-05)
In the title compound, [Cu(C(5)H(4)ClNO)(2)(C(4)H(4)N(2))(H(2)O)(2)](ClO(4))(2), the Cu atom, which lies on an inversion centre, has an octahedral environment. The pyrazine ligand also lies about an inversion centre and links adjacent Cu atoms into a chain running along the b axis;
Cancer research, 52(24), 6936-6939 (1992-12-15)
These studies examined the effect of dicumarol on xanthine dehydrogenase (XDH), an enzyme recently shown to bioreduce mitomycin C. Dicumarol, which has previously been shown to inhibit xanthine oxidase (XO), inhibited both XDH and XO mediated conversion of xanthine to
Cancer research, 53(22), 5470-5474 (1993-11-15)
These studies examined the kinetic and mechanistic parameters of mitomycin C (MMC) bioreduction by xanthine dehydrogenase (XDH), an enzyme recently shown to be capable of MMC activation. The bioreduction of MMC by XDH leads to the formation of 2,7-diaminomitosene (2,7-DM)
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