跳转至内容
Merck

104493

Sigma-Aldrich

氯乙酰氯

98%

别名:

Chloroacetic chloride

登录查看公司和协议定价


About This Item

线性分子式:
ClCH2COCl
CAS号:
分子量:
112.94
Beilstein:
605439
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

蒸汽密度

3.9 (vs air)

蒸汽壓力

60 mmHg ( 41.5 °C)

化驗

98%

折射率

n20/D 1.453 (lit.)

bp

105-106 °C (lit.)

mp

−22 °C (lit.)

密度

1.418 g/mL at 25 °C (lit.)

SMILES 字串

ClCC(Cl)=O

InChI

1S/C2H2Cl2O/c3-1-2(4)5/h1H2

InChI 密鑰

VGCXGMAHQTYDJK-UHFFFAOYSA-N

正在寻找类似产品? 访问 产品对比指南

一般說明

氯乙酰氯被用作氯化试剂、酰化试剂、单氯酮烯的前体,以及环化的合成砌块。

氯乙酰氯在合成二级胺取代的氰基吡唑啉衍生物过程中引起氰基吡唑啉的酰化。

應用

氯乙酰氯可用于聚(甲基丙烯酸缩水甘油酯)的氯乙酰化和化学改性。氯乙酰氯用于研究大鼠和人肝微粒体对氯乙酰胺除草剂的体外代谢。氯乙酰氯用于合成一些具有抗利什曼原虫活性的新型喹啉衍生物

訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Eye Dam. 1 - Skin Corr. 1A - STOT RE 1

標靶器官

Lungs

安全危害

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

212.0 °F - closed cup

閃點(°C)

100 °C - closed cup

個人防護裝備

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Chloroacetyl Chloride
George AO, et al.
eEROS (Encyclopedia of Reagents for Organic Synthesis) (2001)
Jin Hee Ahn et al.
Bioorganic & medicinal chemistry letters, 14(17), 4461-4465 (2004-09-11)
A new series of cyano-pyrazoline derivatives with secondary amine at P-2 site was synthesized through achiral and chiral synthetic methods and evaluated for their ability to inhibit dipeptidyl peptidase IV (DP-IV). Compound 5i revealed good in vivo efficacy (ED50: 4.1
S Coleman et al.
Environmental health perspectives, 108(12), 1151-1157 (2001-01-03)
Acetochlor [2-chloro-N-(ethoxymethyl)-N-(2-ethyl-6-methyl-phenyl)-acetamide], alachlor [N-(methoxymethyl)-2-chloro-N-(2, 6-diethyl-phenyl)acetamide], butachlor [N-(butoxymethyl)-2-chloro-N-(2,6-diethyl-phenyl)acetamide], and metolachlor [2-chloro-N-(2-ethyl-6-methylphenyl)-N-(2-methoxy-1-methylethyl) acetamide] are pre-emergent herbicides used in the production of agricultural crops. These herbicides are carcinogenic in rats: acetochlor and alachlor cause tumors in the nasal turbinates, butachlor causes stomach tumors
Kenawy el-R et al.
Journal of controlled release : official journal of the Controlled Release Society, 50(1-3), 145-152 (1998-08-01)
Polymers with antibacterial activity have been synthesized by chemical modification of poly(glycidyl methacrylate). The glycidyl methacrylate was polymerized by the free radical polymerization technique. The poly(glycidyl methacrylate) was hydrolyzed and was chloroacetylated using chloroacetyl chloride. The chloroacetylated product was modified
Niranjan P Sahu et al.
Bioorganic & medicinal chemistry, 10(6), 1687-1693 (2002-04-09)
Some novel quinoline derivatives were prepared and tested for antileishmanial activity. 2-(2-Methylquinolin-4-ylamino)-N-phenylacetamide (2) was found to be significantly more active than the standard antileishmanial drug sodium antimony gluconate (SAG) in reducing the parasite load both in the spleen and liver

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门