HRAS
Harvey rat sarcoma viral oncogene homolog
别名:
C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, K-RAS, N-RAS, RASH1
物种:
Human HRAS (3265), Rat Hras (293621), dog HRAS (403735), cow HRAS (100298939), naked mole-rat Hras (101716053), chicken HRAS (396229), domestic guinea pig Hras (100735038), sheep HRAS (101104357)
UniProtKB ID:
基因ID:
- Human(3265) Summary: This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene. [provided by RefSeq, Jul 2008]
- Rat(293621) Harvey rat sarcoma virus oncogene
- dog(403735) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
- cow(100298939) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
- naked mole-rat(101716053) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
- chicken(396229) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
- domestic guinea pig(100735038) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
- sheep(101104357) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
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Small Molecule - Antagonist
Antibodies
货号
说明
物种反应性
应用
Monoclonal Anti-HRAS antibody produced in mouse, clone H-RAS-03,
物种反应性
human
应用
western blot
Anti-c-H-Ras (Ab-1) Mouse mAb (F235-1.7.1), liquid, clone F235-1.7.1, Calbiochem®,
物种反应性
human, mouse, rat
应用
Anti-H-Ras Antibody, clone 3B13 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, mouse, rat
应用
ELISA
affinity binding assay
western blot
affinity binding assay
western blot
抗-Ha-Ras抗体（克隆MC57，兔单克隆）, culture supernatant, clone MC57, from rabbit,
物种反应性
human, mouse, rat
应用
western blot
Anti-HRAS antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
esiRNA
货号
说明
物种