89921
(±)-2,4-Dihydroxybutyric acid lithium salt
≥95.0% (GC)
Synonym(s):
2,4-Dihydroxybutanoic acid lithium salt
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About This Item
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Quality Level
Assay
≥95.0% (GC)
application(s)
clinical testing
format
neat
storage temp.
2-8°C
InChI
1S/C4H8O4/c5-2-1-3(6)4(7)8/h3,5-6H,1-2H2,(H,7,8)
InChI key
UFYGCFHQAXXBCF-UHFFFAOYSA-N
Biochem/physiol Actions
Various cases of succinic semialdehyde dehydrogenase deficiency have shown consistently increased amounts of this metabolite, while 2,4-dihydroxybutanoic acid is usually absent in normal human urine extracts or in only trace constituents in neonates.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
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Journal of inherited metabolic disease, 10(4), 367-375 (1987-01-01)
In addition to the previously reported abnormalities, urine extracts from three cases of succinic semialdehyde dehydrogenase deficiency have shown consistently increased amounts of 2,4-dihydroxybutyric acid, and its lactone, and 3-hydroxypropionic acid, metabolites related to the alpha-oxidation of 4-hydroxybutyric acid. Threo-
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