1332000

Hydroxyurea

United States Pharmacopeia (USP) Reference Standard

• Sinónimos: Hydroxycarbamide
• Fórmula lineal: NH₂CONHOH
• Número de CAS: 127-07-1
• Peso molecular: 76.05
• Beilstein: 1741548
• Número MDL: MFCD00007943
• Código UNSPSC: 41116107
• ID de la sustancia en PubChem: 329750138
• NACRES: NA.24

Propiedades

• grado: pharmaceutical primary standard
• familia API: hydroxyurea
• fabricante / nombre comercial: USP
• aplicaciones: pharmaceutical (small molecule)
• Formato: neat
• temp. de almacenamiento: 2-8°C
• cadena SMILES: NC(=O)NO
• InChI: 1S/CH4N2O2/c2-1(4)3-5/h5H,(H3,2,3,4)
• Clave InChI: VSNHCAURESNICA-UHFFFAOYSA-N
• Información sobre el gen: human ... RRM1(6240) , RRM2(6241) , RRM2B(50484)

Descripción

Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Acciones bioquímicas o fisiológicas

Anti-neoplastic. Inactivates ribonucleoside reductase by forming a free radical nitroxide that binds a tyrosyl free radical in the active site of the enzyme. This blocks the synthesis of deoxynucleotides, which inhibits DNA synthesis and induces synchronization or cell death in S-phase.

Nota de análisis

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Otras notas

Sales restrictions may apply.

Información de seguridad

• Pictogramas: GHS08
• Palabra de señalización: Danger
• Frases de peligro: H340,H361
• Consejos de prudencia: P201 - P280 - P308 + P313
• Clasificaciones de peligro: Muta. 1B - Repr. 2
• Código de clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable