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I8140

Sigma-Aldrich

IgG from rabbit serum

technical grade, ≥80% (SDS-PAGE), buffered aqueous solution

Sinónimos:

Rabbit IgG

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About This Item

Número MDL:
MFCD00165673
Código UNSPSC:
12352203
NACRES:
NA.46
En este momento no podemos mostrarle ni los precios ni la disponibilidad

conjugado

unconjugated

Nivel de calidad

200

grado

technical grade

Ensayo

≥80% (SDS-PAGE)

Formulario

buffered aqueous solution

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

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Aplicación

IgG from rabbit serum has been used:
  • as a reference, standard or blocking agent in many immunoassays including dot blots, ELISA, Westerns, IEP, and immunodiffusion assays
  • in arthus reaction[1]
  • in chromatin immunoprecipitation[2]

Acciones bioquímicas o fisiológicas

Immunoglobulin G (IgG) regulates the immune responses such as phagocytosis and is also involved in the development of autoimmune diseases.[3] IgG1 regulates complement fixation in mice.[4]

Forma física

Solution in 0.01 M phosphate buffered saline, pH 7.2, containing 15 mM sodium azide

Nota de preparación

Rabbit IgG is purified via fractionation from pooled normal rabbit serum

Nota de análisis

Immunoelectrophoresis (IEP) is used to establish the identity of the Rabbit IgG. . A single major arc of precipitation in the gamma region is observed versus anti-rabbit whole serum and anti-rabbit IgG. Minor gamma arcs may be present versus anti-rabbit whole serum

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
0000393261
0000362912
0000320936
0000345835
0000320936

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Frances Rena Bahjat et al.
Arthritis and rheumatism, 58(5), 1433-1444 (2008-04-29)
To assess whether R788, an orally bioavailable small molecule inhibitor of spleen tyrosine kinase (Syk)-dependent signaling, could modulate disease in lupus-prone (NZB x NZW)F1 (NZB/NZW) mice via inhibition of Fc receptor (FcR) and B cell receptor signaling. R788 was administered
Elena Matveeva et al.
Cell discovery, 2, 15046-15046 (2016-07-28)
Specialized chromatin structures such as nucleosomes with specific histone modifications decorate exons in eukaryotic genomes, suggesting a functional connection between chromatin organization and the regulation of pre-mRNA splicing. Through profiling the functional location of Poly (ADP) ribose polymerase, we observed
Mhairi Laird et al.
Endocrinology, 158(4), 920-935 (2017-03-23)
Androgens are essential for the normal function of mature antral follicles but also have a role in the early stages of follicle development. Polycystic ovary syndrome (PCOS), the most common cause of anovulatory infertility, is characterized by androgen excess and
Aluya R Oseghale et al.
Blood cells, molecules & diseases, 79, 102345-102345 (2019-07-28)
Pharmacologic induction of fetal hemoglobin (HbF) is an effective strategy for treating sickle cell disease (SCD) by ameliorating disease severity. Hydroxyurea is the only FDA-approved agent that induces HbF, but significant non-responders and requirement for frequent monitoring of blood counts
Lily Chien Wang et al.
DNA repair, 7(12), 1973-1981 (2008-09-13)
Fanconi anemia (FA) is a recessive genetic disorder characterized by hypersensitivity to crosslinking agents that has been attributed to defects in DNA repair and/or replication. FANCD2 and the FA core complex bind to chromatin during DNA replication; however, the role
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Questions

  1. What is the concentration of this IgG?

    1 answer

    1. The protein concentration for I8410 is batch-dependent and ranges from 10.0 - 13.0 mg/mL.

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