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Key Documents

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H8664

Sigma-Aldrich

Steviol

≥98% (HPLC), powder

Sinónimos:

(4α)-13-hydroxykaur-16-en-18-oic acid

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About This Item

Fórmula empírica (notación de Hill):
C20H30O3 · xH2O
Número de CAS:
471-80-7
Peso molecular:
318.45 (anhydrous basis)
MDL number:
MFCD20441965
UNSPSC Code:
12161501
PubChem Substance ID:
329815252
NACRES:
NA.77

assay

≥98% (HPLC)

form

powder

color

white to tan

solubility

DMSO: >10 mg/mL

storage temp.

2-8°C

SMILES string

O.C[C@@]12CCC[C@](C)([C@H]1CC[C@]34CC(=C)[C@](O)(CC[C@@H]23)C4)C(O)=O

InChI

1S/C20H30O3.H2O/c1-13-11-19-9-5-14-17(2,7-4-8-18(14,3)16(21)22)15(19)6-10-20(13,23)12-19;/h14-15,23H,1,4-12H2,2-3H3,(H,21,22);1H2/t14-,15-,17+,18+,19+,20-;/m0./s1

InChI key

SGPAFVVDOPSBEU-CRRYNOPCSA-N

Biochem/physiol Actions

Steviol is an inhibitor of hOAT1 and hOAT3 organic anion transporters. Human organic anion transporter hOAT1 belongs to a superfamily of organic anion transporters, which play critical roles in the body disposition of clinically important drugs including anti-HIV therapeutics, anti-tumor drugs, antibiotics, anti-hypertensives, and anti-inflammatories. Steviol is a useful tool for studying renal drug clearance.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Sigma-Aldrich

N7252

19-Nortestosterone

Stevioside primary reference standard

05420590

Stevioside

Stijn Ceunen et al.
Plant science : an international journal of experimental plant biology, 198, 72-82 (2012-12-04)
The effect of photoperiodism on steviol glycoside (SVgly) accumulation was investigated in Stevia rebaudiana. Topped plants were cultivated to develop new branches under a 16h or 8h photoperiod. During different ontogenetic phases, leaves, stems, lateral shoots, roots and reproductive organs
Ravil N Khaybullin et al.
Bioorganic & medicinal chemistry letters, 22(22), 6909-6913 (2012-10-11)
New derivatives of steviol 1, the aglycone of the glycosides of Stevia rebaudiana, including a novel class of semisynthetic diterpenoids, namely macrocyclic ent-kauranes were synthesized. These compounds possess antituberculosis activity inhibiting the in vitro growth of Mycobacterium Tuberculosis (H37R(V) strain)
Vikas Jaitak et al.
Journal of pharmaceutical and biomedical analysis, 47(4-5), 790-794 (2008-05-06)
A high-performance thin-layer chromatographic (HPTLC) method was developed and validated as per ICH (International Conferences on Harmonization) guidelines for simultaneous quantification of three steviol glycosides, i.e. steviolbioside, stevioside and rebaudioside-A in Stevia rebaudiana leaves. For achieving good separation, mobile phase
Hitesh Kumar et al.
Gene, 492(1), 276-284 (2011-11-01)
Stevia [Stevia rebuaidana (Bertoni); family: Asteraceae] is known to yield diterpenoid steviol glycosides (SGs), which are about 300 times sweeter than sugar. The present work analyzed the expression of various genes of the SGs biosynthesis pathway in different organs of
M S Melis et al.
Brazilian journal of biology = Revista brasleira de biologia, 69(2), 371-374 (2009-08-14)
Stevia rebaudiana, a South American plant normally used as a natural herbal sweetener, has been suggested as exerting beneficial effects on human health, including as an antihypertensive and antihyperglycemic. The present experiment was undertaken to evaluate the renal excretion of
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