B7686

1(S),9(R)-(−)-Bicuculline methchloride

≥97% (HPLC), powder

• Fórmula lineal: C₂₁H₂₀NO₆Cl
• Número de CAS: 38641-83-7
• Peso molecular: 417.84
• MDL number: MFCD00055233
• UNSPSC Code: 12352200
• PubChem Substance ID: 329773300
• NACRES: NA.77

Propiedades

• Quality Level: 100
• assay: ≥97% (HPLC)
• form: powder
• solubility: H₂O: >10 mg/mL
• storage temp.: 2-8°C
• SMILES string: [Cl-].C[N+]1(C)CCc2cc3OCOc3cc2[C@H]1[C@@H]4OC(=O)c5c6OCOc6ccc45
• InChI: 1S/C21H20NO6.ClH/c1-22(2)6-5-11-7-15-16(26-9-25-15)8-13(11)18(22)19-12-3-4-14-20(27-10-24-14)17(12)21(23)28-19;/h3-4,7-8,18-19H,5-6,9-10H2,1-2H3;1H/q+1;/p-1/t18-,19+;/m0./s1
• InChI key: RLJKFAMYSYWMND-GRTNUQQKSA-M

Descripción

Biochem/physiol Actions

1(S),9(R)-(−)-Bicuculline methchloride is a GABA_A receptor antagonist, which blocks Ca²⁺-activated potassium (SK) channels.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the GABAA Receptors and Potassium Channels pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Información de seguridad

• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)