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Merck
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Key Documents

EZML

Millipore

Mouse Leptin ELISA Kit

measures and quantifies Leptin levels in 10 μL serum or plasma

Sinónimos:

Leptin, Obesity factor

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About This Item

UNSPSC Code:
12161503
eCl@ss:
32161000
NACRES:
NA.32

product name

Mouse Leptin ELISA, This Mouse Leptin ELISA is used to measure & quantify Leptin levels in Metabolism & Endocrine & Neuroscience research.

Quality Level

200

species reactivity

mouse

packaging

kit of 1 × 96 wells

parameter

10 μL sample volume (4hr assay)

assay range

accuracy: 87-100%
linearity: 100-111%
sensitivity: 0.05 ng/mL
standard curve range: 0.2-30 ng/mL

technique(s)

ELISA: suitable

input

sample type serum
sample type plasma (K2 EDTA)

UniProt accession no.

P41159
P41160

application(s)

research use

detection method

colorimetric (450nm/590nm)

shipped in

wet ice

storage temp.

2-8°C

Categorías relacionadas

General description

Mouse Leptin ELISA is used to measure and quantify leptin levels in metabolism, endocrine, and neuroscience research. Leptin is a hormone or cytokine derived from adipocytes circulating in the blood. It acts as a regulator of food intake and energy expenditure via the hypothalamus. This hormone plays a role in angiogenesis, lipid and carbohydrate metabolism, and hematopoiesis. Leptin exerts its effects on the cardiovascular, reproductive, and immune systems. The deficiency of leptin in rodents is associated with obesity and insulin resistance.

Application

Mouse Leptin ELISA has been used to determine the levels of leptin in mice serum and plasma.

Disclaimer

For research use only. Not for use in diagnostic procedures.

pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Warning

hcodes

H290,H317

Hazard Classifications

Met. Corr. 1 - Skin Sens. 1

Storage Class

8A - Combustible corrosive hazardous materials

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Effects of castration on insulin levels and glucose tolerance in the mouse differ from those in man.
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Leptin signalling
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Cellular Signalling, 14(8), 655-663 (2002)
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The Journal of physiology, 597(1), 151-172 (2018-10-05)
Leptin is a potent respiratory stimulant. A long functional isoform of leptin receptor, LepRb , was detected in the carotid body (CB), a key peripheral hypoxia sensor. However, the effect of leptin on minute ventilation (VE ) and the hypoxic
Timothy M Griffin et al.
Arthritis and rheumatism, 60(10), 2935-2944 (2009-10-01)
To test the hypothesis that obesity resulting from deletion of the leptin gene or the leptin receptor gene results in increased knee osteoarthritis (OA), systemic inflammation, and altered subchondral bone morphology. Leptin-deficient (ob/ob) and leptin receptor-deficient (db/db) female mice compared
Night eating and obesity in the EP3R-deficient mouse.
Manuel Sanchez-Alavez, Izabella Klein, Sara E Brownell, Iustin V Tabarean et al.
Proceedings of the National Academy of Sciences of the USA null
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