ABN27

Anti-GRIP-1 Antibody, CT

from rabbit, purified by affinity chromatography

• Sinónimos: glutamate receptor interacting protein 1, glutamate receptor-interacting protein 1
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• purified by: affinity chromatography
• species reactivity: rat
• species reactivity (predicted by homology): mouse (based on 100% sequence homology), human (based on 100% sequence homology), chimpanzee (based on 100% sequence homology)
• technique(s): immunohistochemistry: suitable (paraffin); immunoprecipitation (IP): suitable; western blot: suitable
• NCBI accession no.: NP_114458
• UniProt accession no.: P97879
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: rat ... Grip1(84016)

Descripción

General description

Glutamate receptor interacting protein-1 (GRIP-1) is a multi-PDZ domain scaffold protein and a member of the steroid receptor coactivator (SRC) family of proteins. GRIP-1 interacts and maneuvers kinesin heavy chains to dendrites by acting as the power source for AMPA receptors. During initial stages of embryonic development, GRIP-1 is essential for typical cell-matrix interactions.

Specificity

This antibody recognizes GRIP-1 at the C-terminus.

Immunogen

Epitope: C-terminus

KLH-conjugated linear peptide corresponding to the C-terminus of rat GRIP-1.

Application

Detect GRIP-1 using this Anti-GRIP-1 Antibody, C-terminus validated for use in WB, IP, IH(P).

Immunoprecipitation Analysis: 10 µg from a previous lot immunoprecipitated GRIP-1 from rat brain cytosol tissue lysate.

Immunohistochemistry Analysis: 1:300 dilution from a previous lot detected GRIP-1 in rat brain cells.

Research Category
Neuroscience

Research Sub Category
Signaling Neuroscience

Quality

Evaluated by Western Blot in rat brain cytosol tissue lysate.

Western Blot Analysis: 0.05 µg/mL of this antibody detected GRIP-1 on 10 µg of rat brain cytosol tissue lysate.

Target description

~121 kDa observed

Linkage

Replaces: 06-986

Physical form

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
Rat brain cytosol tissue lysate

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable