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Documentos clave

05-384

Sigma-Aldrich

Anti-α-Actinin Antibody, clone AT6/172

clone AT6/172, Upstate®, from mouse

Sinónimos:

Anti-BDPLT15

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

origen biológico

mouse

Nivel de calidad

forma del anticuerpo

purified immunoglobulin

tipo de anticuerpo

primary antibodies

clon

AT6/172, monoclonal

reactividad de especies

rabbit, human, mouse

fabricante / nombre comercial

Upstate®

técnicas

immunocytochemistry: suitable
western blot: suitable

isotipo

IgG1

Nº de acceso NCBI

Nº de acceso UniProt

Condiciones de envío

dry ice

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... ACTN1(87)

Especificidad

Recognizes α-actinin.

Inmunógeno

Human α-actinin

Aplicación

Immunoprecipitation is not recommended
Research Category
Cell Structure
Research Sub Category
Cytoskeleton
This Anti-α-Actinin Antibody, clone AT6/172 is validated for use in IC, WB for the detection of α-Actinin.

Calidad

Routinely evaluated in immunoblot on human A431 cells

Descripción de destino

100 kDa

Forma física

Format: Purified
Please see product datasheet for lot-specific formulation.
Protein A purified

Almacenamiento y estabilidad

Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Nota de análisis

Control
Positive Antigen Control: Catalog #12-301, non-stimulated A431 cell lysate. Add 2.5µL of 2-mercaptoethanol/100µL of lysate and boil for 5 minutes to reduce the preparation. Load 20µg of reduced lysate per lane for minigels.

Información legal

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Never in mitosis gene A related kinase-6 attenuates pressure overload-induced activation of the protein kinase B pathway and cardiac hypertrophy.
Bian, Z; Liao, H; Zhang, Y; Wu, Q; Zhou, H; Yang, Z; Fu, J; Wang, T; Yan, L; Shen, D; Li, H; Tang, Q
Testing null
Requirement of phosphatidylinositol 4,5-bisphosphate for alpha-actinin function
Fukami, K, et al
Nature, 359, 150-152 (1992)
Jing Zong et al.
Laboratory investigation; a journal of technical methods and pathology, 93(10), 1128-1136 (2013-08-21)
Nucleotide-binding oligomerization domain-2 (NOD2, also designated CARD15), a member of the NOD-leucine-rich repeat (LRR) protein family (also called the CATERPILLAR family), is upregulated in atheroma lesions and has an important role in regulating the intracellular recognition of bacterial components by
Identification of genes differentially expressed in mouse mammary epithelium transformed by an activated beta-catenin.
Renou, JP; Bierie, B; Miyoshi, K; Cui, Y; Djiane, J; Reichenstein, M; Shani, M; Hennighausen, L
Oncogene null
Xiaoxiong Liu et al.
Journal of the American Heart Association, 7(13) (2018-06-28)
Carboxyl-terminal modulator protein (CTMP) has been implicated in cancer, brain injury, and obesity. However, the role of CTMP in pathological cardiac hypertrophy has not been identified. In this study, decreased expression of CTMP was observed in both human failing hearts

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