Saltar al contenido
Merck

N-036

Supelco

(±)-Norketamine hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización


About This Item

Fórmula empírica (notación de Hill):
C12H15Cl2NO
Número de CAS:
Peso molecular:
260.16
Código UNSPSC:
41116107
NACRES:
NA.24

grado

certified reference material

Nivel de calidad

Formulario

liquid

Características

Snap-N-Spike®/Snap-N-Shoot®

envase

ampule of 1 mL

fabricante / nombre comercial

Cerilliant®

concentración

1.0 mg/mL in methanol (as free base)

técnicas

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

aplicaciones

forensics and toxicology

Formato

single component solution

temp. de almacenamiento

−20°C

cadena SMILES

Cl.NC1(CCCCC1=O)c2ccccc2Cl

InChI

1S/C12H14ClNO.ClH/c13-10-6-2-1-5-9(10)12(14)8-4-3-7-11(12)15;/h1-2,5-6H,3-4,7-8,14H2;1H

Clave InChI

CLPOJGPBUGCUKT-UHFFFAOYSA-N

Descripción general

Norketamine is the major urinary metabolite of ketamine. This certified Snap-N-Spike® Solution is suitable for numerous GC/MS or LC/MS applications in forensic analysis, urine drug testing, clinical toxicology, and clinical or diagnostic testing. Ketamine, sold as Ketanest®, Ketaset® and Ketalar®, is an NMDA receptor antagonist used for the induction and maintenance of general anesthesia in human and veterinary medicine. The drug is often abused at clubs, raves, or parties for its noted hallucingenic and dissociative properties and prescribed by some doctors as an off-label treatment for depression.

Aplicación


  • Pharmacokinetics of ketamine following a short intravenous infusion to isoflurane-anesthetized New Zealand White rabbits: This study employs (±)-Norketamine hydrochloride to examine the pharmacokinetics of ketamine, providing critical insights into its metabolic pathways and implications for anesthetic use in veterinary medicine (Luca et al., 2020).

  • Pharmacokinetics and Safety of Esketamine in Chinese Patients Undergoing Painless Gastroscopy: Research utilizing (±)-Norketamine hydrochloride explores its pharmacological properties compared to ketamine, enhancing the understanding of its safety and efficacy in clinical settings, which is crucial for the development of anesthetic protocols (Wang et al., 2019).

  • The acute and residual effects of escalating, analgesic-range doses of ketamine on driving performance: This innovative study leverages (±)-Norketamine hydrochloride to investigate the effects of ketamine on motor skills and cognitive functions, contributing to discussions on public safety and clinical use of psychoactive compounds (Hayley et al., 2018).

  • Ketamine metabolites with antidepressant effects: This research highlights the role of (±)-Norketamine hydrochloride in identifying ketamine metabolites with potential antidepressant effects, thus expanding its applications beyond anesthetic use to potentially treat mood disorders (Fassauer et al., 2017).

  • Development of Rapidly Metabolized and Ultra-Short-Acting Ketamine Analogs: Utilizing (±)-Norketamine hydrochloride, this study aims at developing new ketamine analogs that could offer benefits such as reduced side effects and shorter duration of action, pivotal for both clinical and therapeutic applications (Harvey et al., 2015).

Información legal

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Ketalar is a registered trademark of Par Sterile Products, LLC
Ketanest is a registered trademark of Pfizer, Inc.
Ketaset is a registered trademark of Zoetis W LLC
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Órganos de actuación

Eyes,Central nervous system

Código de clase de almacenamiento

3 - Flammable liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

49.5 °F - closed cup

Punto de inflamabilidad (°C)

9.7 °C - closed cup


Elija entre una de las versiones más recientes:

Certificados de análisis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documentos section.

Si necesita más asistencia, póngase en contacto con Atención al cliente

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico