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C-016

Supelco

(−)-Cotinine solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Fórmula empírica (notación de Hill):
C10H12N2O
Número de CAS:
486-56-6
Peso molecular:
176.22
Número CE:
200-659-6
Número MDL:
MFCD00077696
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
329774764
NACRES:
NA.24

grado

certified reference material

Formulario

liquid

Características

SNAP-N-SPIKE®, SNAP-N-SHOOT®

envase

ampule of 1 mL

fabricante / nombre comercial

Cerilliant®

concentración

1.0 mg/mL in methanol

técnicas

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

aplicaciones

forensics and toxicology

Formato

single component solution

temp. de almacenamiento

−20°C

cadena SMILES

CN1C(CCC1=O)c2cccnc2

InChI

1S/C10H12N2O/c1-12-9(4-5-10(12)13)8-3-2-6-11-7-8/h2-3,6-7,9H,4-5H2,1H3/t9-/m0/s1

Clave InChI

UIKROCXWUNQSPJ-VIFPVBQESA-N

Categorías relacionadas

Descripción general

An analytical reference standard of the major urinary metabolite of nicotine. Not only is cotinine a biomarker for users of nicotine products including cigarettes, cigars, and snuff, but it′s also an alkaloid found in tobacco. Suitable uses for this analytical reference standard include as a starting material in calibrators and controls for GC/MS and LC/MS applications in nicotine testing methods or clinical and diagnostic testing of nicotine biomarkers.

Información legal

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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N-076

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Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Órganos de actuación

Eyes

Código de clase de almacenamiento

3 - Flammable liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

49.5 °F - closed cup

Punto de inflamabilidad (°C)

9.7 °C - closed cup

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Satu Kalliola et al.
The Journal of allergy and clinical immunology, 131(3), 730-735 (2013-02-06)
Exposure to tobacco smoke is a well-known risk factor for childhood asthma and reduced lung function, but the effect on airway inflammation in preschool-aged children is unclear. To examine the effect of parental smoking on lung function and fractional concentration
R Machaalani et al.
Toxicology and applied pharmacology, 276(3), 204-212 (2014-03-13)
Smoking during pregnancy is associated with low birth weight, premature delivery, and neonatal morbidity and mortality. Nicotine, a major pathogenic compound of cigarette smoke, binds to the nicotinic acetylcholine receptors (nAChRs). A total of 16 nAChR subunits have been identified
Esther García-Esquinas et al.
Pediatrics, 131(5), e1415-e1423 (2013-04-10)
Active smoking and secondhand smoke (SHS) are known risk factors for kidney disease in adults. We evaluated the association between exposure to active smoking or SHS and kidney function in US adolescents. This is a cross-sectional study in 7516 adolescents
Ana Florescu et al.
Therapeutic drug monitoring, 29(4), 437-446 (2007-08-02)
Exposure to environmental tobacco smoke (ETS) is most often estimated using questionnaires, but they are unreliable. Biomarkers can provide valid information on ETS exposure, the preferred biomarker being cotinine. However, no reference range of hair cotinine exists to distinguish among
Shaan Gellatly et al.
Journal of inflammation research, 13, 175-185 (2020-05-06)
Electronic cigarettes (e-cigs) are relatively new devices that allow the user to inhale a heated and aerosolized solution. At present, little is known about their health effects in the human lung, particularly in the small airways (<2 mm in diameter)
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