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765430

Sigma-Aldrich

Gold nanoparticles

5 nm diameter, carboxylic acid functionalized, PEG 3000 coated, OD 50, dispersion in H2O

Sinónimos:

Gold nanoparticles COOH functionalized, Au NP COOH, Gold Colloid

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About This Item

Código UNSPSC:
12162002
NACRES:
NA.23

Materiales

PEG 3000

Nivel de calidad

100

Formulario

dispersion in H2O
nanoparticles

envase

poly bottle of 1 mL

DO

50

diámetro

5 nm

pH

6.0-8.0 (25 °C)

solubilidad

water: miscible

densidad

1.00 g/cm3

λmáx.

515 nm

grupo funcional

carboxylic acid

temp. de almacenamiento

2-8°C

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Descripción general

Carboxylic acid functionalized GNPs forms conjugates with various protein molecules due to the electrostatic attraction between negatively charged carboxylate groups and positively charged amino groups of protein.

Aplicación

Carboxylic acid functionalized, PEG 3000 coated, OD 50, and H2O dispersed gold nanoparticles (5 nm) can be potentially used in the development of biosensors, cancer-cell imaging, drug delivery, and photothermal therapy.
AuNPs may be used to prepare SARS-CoV-2 conjugate for COVID-19 detection using lateral flow immunoassay technique. It may also be used in the immobilization of antibodies to improve the sensitivity of optical fiber sensors for the screening of COVID-19. It can also be deposited on the titanium electrode for the formation of a miniaturized device for the electrochemical detection of DNA hybridization.
Carboxylic acid group binds with various proteins and is used in targeted drug delivery and gene therapy.
Functionalized Particles have been extensively used to study cellular uptake of nanoparticles and targeted drug delivery.

Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
MKCW9904
MKCS3382
MKCH7216
MKBN9289V
MKBL5787V

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Nóra Adányi et al.
Food chemistry, 267, 10-14 (2018-06-24)
Mycotoxins, present in a wide range of food and feed commodities, are toxic secondary metabolites produced by a number of different fungi. Certain mycotoxins do not readily degrade at high temperatures, therefore are resistant to food processing, and consequently are
Development and clinical application of a rapid IgM-IgG combined antibody test for SARS-CoV-2 infection diagnosis
Li Z, et al.
Journal of Medical Virology, 6, 2071-2071 (2020)
Size-dependent in vivo toxicity of PEG-coated gold nanoparticles
Zhang X, et al.
International journal of nanomedicine, 6, 2071-2071 (2011)
Nishima Wangoo et al.
Journal of colloid and interface science, 323(2), 247-254 (2008-05-20)
We report a novel strategy for the synthesis of aqueous stable, carboxylated gold nanoparticles (GNPs) by using glutamic acid as the reducing agent. The ratio of chloroaurate ions, AuCl(-)(4) to glutamic acid was optimized in the reaction medium to obtain
Recent advances in nanoparticle-based lateral flow immunoassay as a point-of-care diagnostic tool for infectious agents and diseases
Banerjee R and Jaiswal A
Analyst, 143(9), 1970-1996 (2018)
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