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Merck

753610

Sigma-Aldrich

Gold nanoparticles

20 nm diameter, OD 1, stabilized suspension in 0.1 mM PBS, reactant free

Sinónimos:

Au NP, Gold colloid

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About This Item

Número MDL:
Código UNSPSC:
12352302
ID de la sustancia en PubChem:
NACRES:
NA.23
En este momento no podemos mostrarle ni los precios ni la disponibilidad

Nivel de calidad

Formulario

nanoparticles
suspension

concentración

~6.54E+11 particles/mL

DO

1

diámetro

20 nm

λmáx.

518-522 nm

PDI

<0.2

temp. de almacenamiento

2-8°C

cadena SMILES

[Au]

InChI

1S/Au

Clave InChI

PCHJSUWPFVWCPO-UHFFFAOYSA-N

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Descripción general

Gold nanoparticles (AuNPs), 20 nm are colloidal nanomaterials that have quasi-dynamic nature. Their properties include high stability, high surface area, good conductivity, and low toxicity. Their surface chemistry and biocompatibility allow them to be useful in biological applications.[1][2][3][4][5][6]

Aplicación

AuNPs can be used for a variety of applications such as biomedical, electrochemical and energy based devices. They can also be used in drug delivery and biosensing based device fabrication.[1][2][3][4][5][6][7]

Información legal

Product of CytoDiagnostics, Inc.

Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

nwg

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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Certificados de análisis (COA)

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Visite la Librería de documentos

Gold Nanoparticles For Physics, Chemistry And Biology (Second Edition) (2012)
Gold nanoparticles for applications in cancer radiotherapy: Mechanisms and recent advancements
Her S, et al.
Advanced Drug Delivery Reviews, 109(6), 84-101 (2017)
Various methods of gold nanoparticles (GNPs) conjugation to antibodies
Jazayeri MH, et al.
Sensing and Bio-Sensing Research, 9(6), 17-22 (2016)
Gold nanoparticles for applications in energy and environment: synthesis and characterization
Chen Y
Rare Metals, 30(1), 116-120 (2011)
Spectroscopic Study of the Interaction of Carboxyl-Modified Gold Nanoparticles with Liposomes of Different Chain Lengths and Controlled Drug Release by Layer-by-Layer Technology
Kanwa N, et al.
The Journal of Physical Chemistry B, 121(50), 11333-11343 (2017)

Artículos

Steven J. Oldenburg, Ph.D. provides an overview of lateral flow diagnostic assays and discusses the use of ultra-bright reporter particles based on the unique optical properties of gold nanoshells that significantly increase the sensitivity of lateral flow immunoassays.

Steven J. Oldenburg, Ph.D. provides an overview of lateral flow diagnostic assays and discusses the use of ultra-bright reporter particles based on the unique optical properties of gold nanoshells that significantly increase the sensitivity of lateral flow immunoassays.

Sustainable energy sources with high production efficiency are crucial for meeting increasing energy demand.

Steven J. Oldenburg, Ph.D. provides an overview of lateral flow diagnostic assays and discusses the use of ultra-bright reporter particles based on the unique optical properties of gold nanoshells that significantly increase the sensitivity of lateral flow immunoassays.

Ver todo

Questions

1–10 of 14 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  3. If i want to concentrate or isolate gold mannan particles and remove any unlabeled mannan what filtration or centrifugation conditions should be used.

    1 answer
    1. This product is comprised of stabilized gold nanoparticles in 0.1 mM PBS. There is no mannan present. The material may be concentrated by centrifugation. Note that aggregation may become an issue if the particles are removed from the stabilizing solution.

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  4. How does the storage temperature relate to shipping conditions?

    1 answer
    1. The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment.

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  5. How do you attach gold nanoparticles to oligos?

    1 answer
    1. To attach gold nanoparticles to oligos please view the information in the attached reference - Bioconjug Chem. 2011 Apr 20;22(4):794-807. Epub 2011 Mar 28.

      Helpful?

  6. How do you attach gold nanoparticles to peptides and peptide conjugates?

    1 answer
    1. To view information on how to attach gold nanoparticles to peptides and peptide conjugates, please view the information in the reference - Rosenthal, S. J. and Wright, D. W. (Eds.). (2005), p. 91-92. NanoBiotechnology Protocols. New Jersey. Humana Press.

      Helpful?

  7. Can the Gold nanoparticles be frozen?

    1 answer
    1. No, the Gold nanoparticles should not be frozen.  If frozen, the gold nanoparticles will irreversibly aggregate, turning the solution clear.

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  8. Do I need to wash my gold nanoparticles?

    1 answer
    1. For most applications, our gold nanoparticles can be used without any additional washing steps. If you have a sensitive application that requires additional washing the best way to do so is by either centrifugation or filtration.

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  9. How do you attach gold nanoparticles to glass?

    1 answer
    1. To view the procedure on how to attach gold nanoparticles to glass please view information in the reference - Journal of Atomic, Molecular, and Optical PhysicsVolume 2012 (2012). Article ID 683830, 6 pagesdoi:10.1155/2012/683830

      Helpful?

  10. Which gold nanoparticle size should I choose for my application?

    1 answer
    1. The size of gold nanoparticle to use is very depandent upon the intended application. Generally, smaller particles offer better sensitivity in applications such as immunogold labeling due to less steric hindrance and the ability to bind more gold nanoparticles to the desired target. Small gold nanoparticles are less visible than larger particles, however, which must also be taken into account.As an application example, particles with a size between 30-50nm are particularly useful for the development of rapid tests such as lateral flow assays.

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