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431362

Sigma-Aldrich

Hydroxylamine hydrochloride

99.999% trace metals basis

Sinónimos:

Hydroxylammonium chloride

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About This Item

Fórmula lineal:
NH2OH · HCl
Número de CAS:
5470-11-1
Peso molecular:
69.49
Beilstein:
3539763
Número CE:
226-798-2
Número MDL:
MFCD00051089
Código UNSPSC:
12352301
ID de la sustancia en PubChem:
24867012
NACRES:
NA.22
En este momento no podemos mostrarle ni los precios ni la disponibilidad

grado

ACS reagent (specifications)

Nivel de calidad

200

Ensayo

99.999% trace metals basis

Formulario

crystals

impurezas

≤0.005% S compounds
≤0.25 meq/g Titr. free acid
<10 ppm total metallic impurities

residuo de ign.

≤0.05%

pH

2.5-3.5 (20 °C, 50 g/L)

mp

155-157 °C (dec.) (lit.)

densidad

1.67 g/mL at 25 °C (lit.)

trazas de catión

Fe: ≤5 ppm
NH4+:, passes test
heavy metals: ≤5 ppm

cadena SMILES

Cl.NO

InChI

1S/ClH.H3NO/c;1-2/h1H;2H,1H2

Clave InChI

WTDHULULXKLSOZ-UHFFFAOYSA-N

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Aplicación

Reactant for preparation of:
  • Organosilane amines as potent inhibitors and structural probes of influenza A virus M2 proton channel[1]
  • Lamellarin D analogues as inibitors of topoisomerase I and potential antitumor agents[2]
  • Azapeptide tocolytic agents as inhibitors of prostaglandin F2a receptor for preventing preterm labor[3]
  • Thiazolidinones spiro-fused to indolin-2-ones as potent and selective inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatase B[4]
  • Orally bioavailable quinoline-based antidiabetic dipeptidyl peptidase IV inhibitors targeting Lys554[5]
  • Pyrimidine nucleoside derivatives with nitric oxide donors as antiviral agents[6]
  • Benzyladenosine compounds targeting adenosine A2A receptor and adenosine transporter for neuroprotection[7]
  • Naphthol derivatives as inhibitors of the vanilloid receptor TRPV1 with improved potency in rat cystometry models of urinary incontinence[8]

Acciones bioquímicas o fisiológicas

Inhibidor MAO; inhibe la agregación de plaquetas.

Características y beneficios

Meets A.C.S. reagent specifications.

Palabra de señalización

Warning

Clasificaciones de peligro

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Carc. 2 - Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 Oral

Órganos de actuación

spleen

Código de clase de almacenamiento

4.1A - Other explosive hazardous materials

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificados de análisis (COA)

Lot/Batch Number
MKCV2599
MKCR5075
MKCS5686
MKCM6407
MKCJ7604

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Hydroxylamine (50% solution in water) for synthesis

Sigma-Aldrich

8.14441

Hydroxylamine

2-Keto-3-deoxyoctonate ammonium salt &#8805;97%

Sigma-Aldrich

K2755

2-Keto-3-deoxyoctonate ammonium salt

Lizethly Cáceres-Jensen et al.
International journal of environmental research and public health, 18(12) (2021-07-03)
The sorption behavior of 2,4-dichlorophenoxyacetic acid (2,4-D) in the abundant agricultural volcanic ash-derived soils (VADS) is not well understood despite being widely used throughout the world, causing effects to the environment and human health. The environmental behavior and risk assessment
Klaus Urbahns et al.
Bioorganic & medicinal chemistry letters, 21(11), 3354-3357 (2011-05-03)
We have identified naphthol derivatives as inhibitors of the vanilloid receptor TRPV1 by high throughput screening. The initial lead showed high clearance in rats and has been optimized by enhancing the acidity of the phenol group. Compound 6b has reduced
Carine B Bourguet et al.
Journal of medicinal chemistry, 54(17), 6085-6097 (2011-07-22)
The prostaglandin-F2α (PGF2α) receptor (FP) was targeted to develop tocolytic agents for inhibiting preterm labor. Azabicycloalkane and azapeptide mimics 2-10 were synthesized based on the (3S,6S,9S)-indolizidin-2-one amino acid analogue PDC113.824 (1), which was shown to modulate FP by a biased
Salvatore Cananzi et al.
Bioorganic & medicinal chemistry, 19(16), 4971-4984 (2011-07-26)
A novel 5-oxa-6a,8-diazaindeno[2,1-b]phenanthren-7-one scaffold was designed and synthesized as an active analogue of the cytotoxic marine alkaloid Lamellarin D. The design was based on molecular modeling of the site of interaction of Lamellarin D with DNA-topoisomerase I cleavable complex, whereas
Jun Wang et al.
Journal of the American Chemical Society, 133(35), 13844-13847 (2011-08-09)
We describe the use of organosilanes as inhibitors and structural probes of a membrane protein, the M2 proton channel from influenza A virus. Organosilane amine inhibitors were found to be generally as potent as their carbon analogues in targeting WT
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Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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