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SAB4503300

Sigma-Aldrich

Anti-TAS1R3 antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Sweet taste receptor T1R3

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

Pricing and availability is not currently available.

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 93 kDa

species reactivity

human

concentration

~1 mg/mL

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This Item
TMO382099-0250TMO382099-1000TMO312085-0004
capacity

500 mL

capacity

250 mL

capacity

1000 mL

capacity

125 mL

manufacturer/tradename

Nalgene 382099-0500

manufacturer/tradename

Nalgene 382099-0250

manufacturer/tradename

Nalgene 382099-1000

manufacturer/tradename

Nalgene 312085-0004

packaging

case of 48 ea

packaging

case of 72 ea

packaging

case of 24 ea

packaging

case of 500 ea

volume

500 mL

volume

250 mL

volume

1000 mL

volume

125 mL

General description

Taste receptor family 1 member 3 (TAS1R3) gene encodes for sweet taste receptor T1R3 protein. T1R3 protein belongs to the family of 3 subtypes of G-protein coupled receptors (GPCRs). This protein is localized in the taste bud cells of the oral cavity. The TAS1R3 gene is mapped on the human chromosome at 1p36.33.

Immunogen

The antiserum was produced against synthesized peptide derived from human TAS1R3.

Immunogen Range: 326-375

Application

Anti-TAS1R3 antibody produced in rabbit has been used in immunohistochemistry and immunocytochemistry.[1]

Biochem/physiol Actions

Sweet taste receptor T1R3 protein plays a role in membrane glucose sensing and regulates glucose homeostasis in endocrine cells..

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Tas1r3, encoding a new candidate taste receptor, is allelic to the sweet responsiveness locus Sac.
Max, et al.
Nature Genetics, 28, 58-63 (2019)
Mariam Raliou et al.
Neuroscience letters, 451(3), 217-221 (2009-01-17)
Monosodium glutamate as well as metabotropic and ionotropic glutamate receptor agonists have been reported to be perceived as umami by humans. In spite of the fact that Tas1R1-Tas1R3 has been shown to mediate most of the glutamate taste sensation in
Marco Tizzano et al.
Chemical senses, 40(9), 655-660 (2015-09-25)
The morphology of the vallate papillae from postmortem human samples was investigated with immunohistochemistry. Microscopically, taste buds were present along the inner wall of the papilla, and in some cases in the outer wall as well. The typical taste cell
Vladimir O Murovets et al.
PloS one, 10(6), e0130997-e0130997 (2015-06-25)
The G-protein-coupled sweet taste receptor dimer T1R2/T1R3 is expressed in taste bud cells in the oral cavity. In recent years, its involvement in membrane glucose sensing was discovered in endocrine cells regulating glucose homeostasis. We investigated importance of extraorally expressed

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