Skip to Content
Merck
All Photos(2)

Key Documents

View All Documentation

D5751

Sigma-Aldrich

Blue Dextran

Void volume marker for gel filtration columns.

Synonym(s):

Dextran blue from Leuconostoc mesenteroides

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

CAS Number:
87915-38-6
MDL number:
MFCD00130661
UNSPSC Code:
12352200
NACRES:
NA.25

biological source

non-animal source

form

powder

quality

200

mol wt

2,000,000

technique(s)

affinity chromatography: suitable

suitability

suitable for GFC marker

Looking for similar products? Visit Product Comparison Guide

General description

Blue Dextran is a soluble derivative of dextran. Its structure includes triazinyl dye Cibacron blue F3GA covalently bound to high molecular weight (2000 kDa) dextran. Blue Dextran is generally used as a marker to determine void volume in gel filtration chromatography columns.

Application

Blue Dextran has been used for calibration of size exclusion chromatography (SEC) column. It has also been used in Dextran blue permeability assays to determine the integrity of co-cultures containing epithelial cells. Blue dextran may be used in affinity chromatography, gel filtration chromatography, protein chromatography, and molecular weight markers. Blue dextran is also suitable to study Alzheimer′s disease.

Preparation Note

Prepared from dextran with an average mol. wt. of 2,000,000.

Analysis Note

degree of substitution: 0.10 to 0.12 mmol Cibracon Blue per gram of dextran

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 2

1 of 2

Gel Filtration Cal Kit Low Molecular Weight Cytiva 28-4038-41

GE28-4038-41

Gel Filtration Cal Kit Low Molecular Weight

USP

USP

1179800

Dextran Vo Marker

Hushan Yuan et al.
Nature protocols, 13(2), 392-412 (2018-01-26)
Feraheme (FH) nanoparticles (NPs) have been used extensively for treatment of iron anemia (due to their slow release of ionic iron in acidic environments). In addition, injected FH NPs are internalized by monocytes and function as MRI biomarkers for the
Elementary steps in synaptic transmission revealed by currents through single ion channels.
B Sakmann
Bioscience reports, 12(4), 237-262 (1992-08-01)
Catherine Chiu et al.
Fluids and barriers of the CNS, 9(1), 3-3 (2012-01-25)
Amyloid accumulation in the brain parenchyma is a hallmark of Alzheimer's disease (AD) and is seen in normal aging. Alterations in cerebrospinal fluid (CSF) dynamics are also associated with normal aging and AD. This study analyzed CSF volume, production and
Liguo Zhang et al.
Journal of colloid and interface science, 368(1), 648-654 (2011-12-27)
The objective is to investigate the influence of sonication on the mechanical and release properties of hydrogel capsules. A new fabrication process is developed to fabricate millimetric capsules made of a highly-viscous liquid core protected by a thin hyperelastic alginate
Osao Adachi et al.
Bioscience, biotechnology, and biochemistry, 74(12), 2438-2444 (2010-12-15)
The membrane fraction of Gluconobacter oxydans IFO 3244, involving membrane-bound quinoprotein quinate dehydrogenase and 3-dehydroquinate dehydratase, was immobilized into Ca-alginate beads. The Ca-alginate-immobilized bacterial membrane catalyzed a sequential reaction of quinate oxidation to 3-dehydroquinate and its spontaneous conversion to 3-dehydroshikimate
View All Related Papers

Protocols

HPLC Analysis of Glycans

Uncover how HPLC analysis of glycans helps researchers analyze glycan structures and glycoforms & find products to assist in your glycan analysis methods.

HPLC Analysis of Glycans

Uncover how HPLC analysis of glycans helps researchers analyze glycan structures and glycoforms & find products to assist in your glycan analysis methods.

HPLC Analysis of Glycans

Uncover how HPLC analysis of glycans helps researchers analyze glycan structures and glycoforms & find products to assist in your glycan analysis methods.

HPLC Analysis of Glycans

Uncover how HPLC analysis of glycans helps researchers analyze glycan structures and glycoforms & find products to assist in your glycan analysis methods.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service