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Key Documents

D4772

Sigma-Aldrich

Blue Dextran

BioReagent

Synonym(s):

Dextran blue from Leuconostoc mesenteroides

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.25

product line

BioReagent

Quality Level

form

powder

mol wt

~2,000,000

packaging

vial of 50 mg

storage temp.

−20°C

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General description

Blue dextran is a derivative of dextran and a high molecular weight glucose polymer.

Application

Blue Dextran has been used as a single-phase fluid dye in the mass flow capability of hollow microneedle (HMN). It has also been used as a standard in gel filtration chromatography.

Biochem/physiol Actions

Blue dextran is used in affinity chromatography, gel filtration chromatography, protein chromatography and molecular weight markers. Blue dextran has been used to study Alzheimer′s disease.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Synthesis and characterization of blue dextrans
Viet D, et al.
Carbohydrate Polymers, 74(3), 372-378 (2008)
D L Roerig et al.
The American journal of physiology, 262(3 Pt 2), H728-H733 (1992-03-01)
We investigated the uptake and efflux of Blue Dextran in the isolated perfused rabbit lung. Blue Dextran is a high-molecular-weight glucose polymer (original mol wt 2 x 10(6) g/mol) containing covalently bonded Reactive Blue 2 dye (approximately mmol/g dextran). This
Risa Nobuta et al.
Nucleic acids research, 48(18), 10441-10455 (2020-09-18)
Comprehensive genome-wide analysis has revealed the presence of translational elements in the 3' untranslated regions (UTRs) of human transcripts. However, the mechanisms by which translation is initiated in 3' UTRs and the physiological function of their products remain unclear. This
Raja Ghosh et al.
Journal of chromatography. A, 1618, 460892-460892 (2020-01-30)
We discuss how the efficiency of a chromatography device could be enhanced by incorporating a new feature which ensures flow uniformity. The overall flow of fluid within the device, which has a cuboid shape, could be visualized as a combination
Halldor Felde Berg et al.
Reproduction in domestic animals = Zuchthygiene, 55(3), 401-404 (2020-01-10)
An extended lifespan of spermatozoa following artificial insemination (AI) can make the timing of insemination less critical, as previously demonstrated with immobilized spermatozoa that are gradually released from an alginate gel. The purpose was to examine the in vivo dissolution

Protocols

Gel filtration chromatography is an established method for determining the size and molecular mass of proteins.

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